Grass Sensitisation and Allergic Rhinitis in Thai Patients
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Prisijungti Registracija
Nuoroda įrašoma į mainų sritį
StatusasBaigta
Rėmėjai
Mahidol University
Bendradarbiai
National Research Council of Thailand
KLINIKINIS TYRIMAS: NCT01686022
BioSeek: NCT01686022
Raktažodžiai
Santrauka
Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens. Outdoor allergen can be divided into grass, tree, or weed. The type of grass or weed are different in various part of the world. The allergens from grass and weed has never been studied in Thailand. This study will find the major allergen from Bermuda grass, Johnson grass, Para grass, sedge, and ragweed, which are very common in Thailand. In addition, the investigators will study about the cross-reactivity among these group of allergen.
apibūdinimas
To find the major allergen of grass and weed, the serum of patients will be used to bind with the allergen extract by immunoblot study.
The ELISA-inhibition will be used to study about cross-reactivity among various kinds of grass and weed.
Datos
| Paskutinį kartą patikrinta: | 08/31/2016 |
| Pirmasis pateikimas: | 09/11/2012 |
| Numatytas registravimas pateiktas: | 09/13/2012 |
| Pirmas paskelbtas: | 09/16/2012 |
| Paskutinis atnaujinimas pateiktas: | 09/12/2016 |
| Paskutinis atnaujinimas paskelbtas: | 09/13/2016 |
| Faktinė studijų pradžios data: | 09/30/2012 |
| Numatoma pirminio užbaigimo data: | 09/30/2015 |
| Numatoma studijų užbaigimo data: | 09/30/2015 |
Būklė ar liga
Allergy to Grass Pollen
Allergic Rhinitis Due to Weed Pollens
Intervencija / gydymas
Other: Pollen Allergy
Fazė
-
Rankų grupės
| Ranka | Intervencija / gydymas |
|---|---|
| Pollen Allergy Pollen allergy and control will have the same intervention, ie. Skin prick test and collect serum samples.Then measure the specificIgE, immunoblot, and ELISA inhibition | Other: Pollen Allergy serum specific IgE binds to grass extract by immunoblot |
Tinkamumo kriterijai
| Amžius, tinkami studijuoti | 10 Years Į 10 Years |
| Tinkamos studijoms lytys | All |
| Mėginių ėmimo metodas | Non-Probability Sample |
| Priima sveikus savanorius | Taip |
| Kriterijai | Inclusion Criteria: - Allergic rhinitis patients age 10-50 years old - Control: healthy volunteer age 18-50 years old Exclusion Criteria: - Chronic illness such as cardiovascular diseases, liver diseases - History of anaphylaxis - Pregnancy |
