Anesthetic Management in Fetoscopic Surgery and Incidence of Complications

Straipsnius versti gali tik registruoti vartotojai

Prisijungti Registracija

Nuoroda įrašoma į mainų sritį

StatusasBaigta

Rėmėjai

Mahidol University

KLINIKINIS TYRIMAS: NCT02434926

BioSeek: nct02434926

Raktažodžiai

urinary bladder neck obstruction

Santrauka

Fetoscopic surgery has been acknowledged to be a reliable procedure to correct several congenital anomalies e.g. shunt insertion in fetal bladder outlet obstruction, laser ablation of vessels in twin-twin transfusion syndrome (TTTS), balloon occlusion in congenital diaphragmatic hernia etc. The technique involves an introduction of small-caliber instruments into the amniotic cavity under ultrasound guidance. This procedure can be successfully done under either general anesthesia, regional anesthesia or local anesthesia with sedation. Each technique has both advantages and drawbacks.

Several complications related to anesthetic after fetoscopic surgery can occur. For instance, pulmonary edema which is caused by intravenous fluid loading, irrigation fluid absorption or fluid flow through myometrium venous channel. Besides, maternal hypotension intraoperatively can arise from spinal anesthesia.

The aim of the study is to report choice of anesthesia using in fetoscopic surgery in the tertiary care institute (Siriraj hospital) and incidence of complications which may relate to different anesthetic techniques.

apibūdinimas

The quantity and types of medications using in different anesthetic technique will be gathered including opioid, benzodiazepine, propofol, detail of drugs making fetal paralysis, amount of local anesthetic drug in spinal anesthesia etc. Tocolytic drug will also be recorded eg. terbutaline, nifedipine or magnesium sulfate. These drugs have been generally known that may cause hypotension or pulmonary edema.

In intraoperative period, the investigators emphasize in the incidence of hypotension and other possible complications such as pulmonary aspiration, failed intubation, maternal desaturation or maternal bradycardia. Volume of intravenous fluid administered and amount of irrigation fluid will also be recorded.

Maternal and fetal outcome in recovery room and in postoperative period will be collected.

Datos

Paskutinį kartą patikrinta:	07/31/2016
Pirmasis pateikimas:	04/25/2015
Numatytas registravimas pateiktas:	04/29/2015
Pirmas paskelbtas:	05/05/2015
Paskutinis atnaujinimas pateiktas:	08/10/2016
Paskutinis atnaujinimas paskelbtas:	08/11/2016
Faktinė studijų pradžios data:	04/30/2015
Numatoma pirminio užbaigimo data:	12/31/2015
Numatoma studijų užbaigimo data:	01/31/2016

Būklė ar liga

Fetoscopy

Anesthetic Complications

Pregnancy

Fazė

Tinkamumo kriterijai

Tinkamos studijoms lytys	Female
Mėginių ėmimo metodas	Non-Probability Sample
Priima sveikus savanorius	Taip
Kriterijai	Inclusion Criteria: - pregnant women who received intrauterine minimally invasive surgery from the past until 30 Nov 2015 Exclusion Criteria: - pregnant women who received intrauterine minimally invasive surgery which was not anesthetized by anesthesiologist.

Rezultatas

Pirminės rezultatų priemonės

1. Type of anesthetic techniques used in fetoscopic surgery [in operating theatre]

Type of anesthetic techniques eg. general anesthesia, regional anesthesia, local anesthesia with sedation.

Antrinės rezultatų priemonės

1. Types and quantity of anesthetic medications used [in operating theatre]

Types and quantity of anesthetic medications used for anesthetize patients in different anesthetic techniques.

2. Incidence of complications [in operating theatre]

Intraoperative complications eg. failed intubation, aspiration, hypotension from spinal anesthesia, high spinal block, desaturation etc.

3. Incidence of complications [after surgery till patients discharge from the hospital]

Complications occurring postoperatively include pulmonary edema, fatal death etc.

Anesthetic Management in Fetoscopic Surgery and Incidence of Complications

Raktažodžiai

edema

hernia

dantų ėduonis

urinary bladder neck obstruction

pulmonary edema

bradycardia

hypotension