Bio-availability of a New Liquid Tumeric Extract
Raktažodžiai
Santrauka
apibūdinimas
Twelve healthy participants enrolled to the study. All volunteers will have pre study evaluation to confirm healthy state. After enrollment, each participant will be tested twice, one with the liquid tumeric/curcumin (study drug) and once with the curcumin powder (control). The days of testing will be on two days, separated by two weeks wash-out period. The participants will be assigned to randomly receive study drug or control on the 1st day, with the other regimen administered at the 2nd day. Both study drug and control will be diluted in 150ml of water. The doe of study drug will be escalated from 30 drops (4 participants), 50 drops (4 participants) and 70 drops (4 participants). Blood sample will be collected at 0,0.25,0.5,0.75,1,2,3,4,5,6,8h post drug. Quantization of curcumin plasma levels will be done by the high pressure liquid chormatography method. A biomarker for the potential effect of curcumin, platelet function pre and post curcumin consumption will be tested.
Datos
Paskutinį kartą patikrinta: | 07/31/2015 |
Pirmasis pateikimas: | 10/09/2007 |
Numatytas registravimas pateiktas: | 10/09/2007 |
Pirmas paskelbtas: | 10/10/2007 |
Paskutinis atnaujinimas pateiktas: | 08/18/2015 |
Paskutinis atnaujinimas paskelbtas: | 08/19/2015 |
Būklė ar liga
Intervencija / gydymas
Drug: liquid tumeric/curcumin extract
Fazė
Tinkamumo kriterijai
Amžius, tinkami studijuoti | 18 Years Į 18 Years |
Tinkamos studijoms lytys | All |
Priima sveikus savanorius | Taip |
Kriterijai | Inclusion Criteria: - Complete Healthy - Able to attend two full days of study |