Curcuma Extract Beneficial for Muscle Damage
Raktažodžiai
Santrauka
apibūdinimas
Muscle damage is a clinical problem caused by the adaptation process in strenuous exercise of soccer athletes which free radical is the main culprit of the damage. There is a significant increment of muscle damage after strength exercise using leg press. Physical exercise leads to inflammation process in endothelial cells of blood vessel which can be marked by releasing cytokine. Interleukin-6 (IL-6) is one of cytokine pro-inflammation and this marker is used as an indicator for inflammation of micro-trauma in muscle during strenuous exercise.
Normally, free radical generation will be stabilized by endogenous antioxidant secretion such as superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase; nevertheless, body needs exogenous antioxidant to support endogenous antioxidant as a scavenger of free radical in such condition.
Muscle damage due to the strenuous exercise should be managed to avoid the pain feeling and subsequently decrease athlete performances. Some previous studies used herbs such as ginger (Zingiber officinale), ginseng (Panax quinquefolium), and Curcuma to relieve the muscle damage and inflammation resulting from high-intensity exercise.The Curcuma extract treatment to the athlete gained lack of success; therefore, supplementation to food products might use to increase acceptability. Ice cream is one of the products, which has a broad segment market and every single person regardless of age is fond of it.
Curcumin is an antioxidant substance contained in Curcuma and it has better antioxidant capacity compared to the other component in Curcuma such as demetoksicurcumin and bisdemetoksicurcumin.Besides, curcumin has an efficient reaction with superoxide radicals as well as lipid antioxidants has, and the reaction leads to superoxide catalytic degradation in which curcumin represents as a superoxide dismutase. This study aimed to examine the Curcuma extract effect which has been supplemented to own-made ice cream in muscle damage and inflammation of soccer athletes after having strenuous exercise.
Datos
Paskutinį kartą patikrinta: | 05/31/2020 |
Pirmasis pateikimas: | 06/10/2020 |
Numatytas registravimas pateiktas: | 06/17/2020 |
Pirmas paskelbtas: | 06/18/2020 |
Paskutinis atnaujinimas pateiktas: | 06/17/2020 |
Paskutinis atnaujinimas paskelbtas: | 06/18/2020 |
Faktinė studijų pradžios data: | 04/07/2019 |
Numatoma pirminio užbaigimo data: | 07/07/2019 |
Numatoma studijų užbaigimo data: | 07/28/2019 |
Būklė ar liga
Intervencija / gydymas
Dietary Supplement: Ice cream
Fazė
Rankų grupės
Ranka | Intervencija / gydymas |
---|---|
Placebo Comparator: Control Group treated by ice cream without any Curcuma extract supplementation | |
Experimental: Treatment Group treated by ice cream supplemented by Curcuma extract |
Tinkamumo kriterijai
Amžius, tinkami studijuoti | 14 Years Į 14 Years |
Tinkamos studijoms lytys | Male |
Priima sveikus savanorius | Taip |
Kriterijai | Inclusion Criteria: - male - 14-18 year-old - does not have an acute and chronic - hemoglobin level ≥13 g/L - nutrition status normal (BMI >18.5-25.0) - no coffee consumption - no alcohol consumption - no drugs consumption - no smoking - no vitamin and other supplements consumption at least two weeks before this study was conducted - no additional exercise except the programmed exercise Exclusion Criteria: - Subject did not comply the procedure of the study |
Rezultatas
Pirminės rezultatų priemonės
1. Lactic acid change [21 days]
2. Hemoglobin change [21 days]
3. IL-6 change [21 days]
4. Creatinine kinase change [21 days]