Atrial myxoma occurring 15 years after subtotal resection of cerebellar hemangioblastoma.

A 51-year-old female, with a past medical history of resection of cerebellar hemangioblastoma, presented with an atrial tumor detected by sonography after undergoing a series of examinations for fever of unknown origin and subsequent symptoms of heart failure. After removing the atrial tumor, the histological findings demonstrated myxoma. Immunohistopathological study showed that the tumor cells in both the hemangioblastoma and the myxoma had strong cytoplasmic immunoreactivity for vascular endothelial growth factor. Hemangioblastoma associated with myxoma is extremely rare, and was probably a random occurrence in this case.