Zhongguo Zhongyao Zazhi 2009-Sep
[Caffeoylquinic acid derivatives from leaves of Lonicera japonica].
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OBJECTIVE
To study the caffeoylquinic acid derivatives from the leaves of Lonicera japonica.
METHODS
The compounds were isolated by column chromatography and identified on the basis of physico-chemical constants and spectral analysis.
RESULTS
Five caffeoylquinic acid derivatives were isolated,and their structures were identified as 3,4-di-O-caffeoyl quinic acid methyl ester (1), 5-O-caffeoyl quinic acid methyl ester (2), 3,4-di-O-caffeoyl quinic acid (3), 1,3-di-O-caffeoyl quinic acid (4) and chlorogenic acid (5), respectively.
CONCLUSIONS
Compounds 2, 4 were obtained from this genus for the first time. Compounds 1, 3 were obtained from this plant for the first time.
