[Sesquiterpenes of Chloranthus serratus Root].

OBJECTIVE

To study sesquiterpenes from the root of Chloranthus serratus.

METHODS

The sesquiterpenes of Chloranthus serratus were isolated and purified by various chromatographic techniques, such as silica gel, Sephadex LH-20 and preparative HPLC. The structures of these isolated compounds were identified by spectroscopic analysis.

RESULTS

Ten sesquiterpenes were isolated and identified as follows: 1β, 8β-dihydroxy-eudesman-4 (15), 7 (11) -dien-8α, 12-olide (I), curcolonol (II), 4β, 8β-dihydroxy-5α (H) -eudesm-7 (11) -en-8, 12-olide (III), 1β, 8,β-dihydroxy-eudesman-3, 7 (11) -dien-8α, 12-olide (IV), multistalactone E (V), zedoarofuran (VI), 8β,9α-dihydroxylindan-4(5), 7(11) -dien-8α,12-olide(VII), serralactone A (VIII), 8-epi-ivangustin (IX), and chloranthalactone E (X ).

CONCLUSIONS

Compounds I, II, IV - VII, IX and X are isolated from Chloranthus serratus for the first time.