Planta Medica 2003-Jan
The vasorelaxant activity of marrubenol and marrubiin from Marrubium vulgare.
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Crude extracts of the aerial parts of Marrubium vulgare show a potent in vitro inhibition of KCl-induced contraction of rat aorta. Bio-guided fractionations, spectroscopic analysis and chemical derivatization revealed the furanic labdane diterpenes marrubenol and marrubiin as the most active compounds.
