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achlorhydria/protease
Nuoroda įrašoma į mainų sritį
4 rezultatus
Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations.
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Prisijungti Registracija
Since its introduction in 1987, zidovudine monotherapy has been the treatment of choice for patients with HIV infection. Unfortunately it has been established that the beneficial effects of zidovudine are not sustained due to the development of resistant viral strains. This has led to the strategy
Meal Effects Confound Attempts to Counteract Rabeprazole-Induced Hypochlorhydria Decreases in Atazanavir Absorption.
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Prisijungti Registracija
Clinically relevant pharmacokinetic interactions exist between gastric acid-reducing agents and certain weakly basic drugs that rely on acidic environments for optimal oral absorption. In this study, we examine whether the administration of betaine hydrochloride under fed conditions can enhance the
Therapeutic drug monitoring of atazanavir: surveillance of pharmacotherapy in the clinic.
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Prisijungti Registracija
BACKGROUND
Therapeutic failure with antiretroviral therapy (ART) is a substantial issue where viral rebound, viral resistance and drug-related toxicity remain serious concerns. Drug exposure-response relationships have been described for the protease inhibitors, pharmacokinetic variability is
Macroautophagy is defective in mucolipin-1-deficient mouse neurons.
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Mucolipidosis type IV is a neurodegenerative lysosomal disease clinically characterized by psychomotor retardation, visual impairment, and achlorhydria. In this study we report the development of a neuronal cell model generated from cerebrum of Mcoln1(-/-) embryos. Prior functional characterization
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