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alpinumisoflavone/derris

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StraipsniaiKlinikiniai tyrimaiPatentai
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Alpinumisoflavone inhibits osteoclast differentiation and exerts anti-osteoporotic effect in ovariectomized mice.

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Alpinumisoflavone (AIF), a naturally occurring flavonoid compound exacted from Derris eriocarpa, has been found to have a number of pharmacological activities. However, its role in bone disorder has not been investigated. The aim of this study is to evaluate the osteoprotective effect of AIF on
Alpinumisoflavone (AIF) is a naturally occurring flavonoid that is a major bioactive component of the medicinal plant Derris eriocarpa. In this study we evaluated the antimetastatic effect of AIF and investigated the underlying mechanism of action using in vitro and in vivo models of melanoma. We

Alpinumisoflavone Inhibits Tumor Growth and Metastasis in Papillary Thyroid Cancer via Up-regulating miR-141-3p.

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Alpinumisoflavone (AIF) as principal active ingredient of traditional Chinese herb Derris eriocarpa exerts a broad spectrum of anti-cancer activities against solid tumors. However, little is known about the effect of AIF on Papillary Thyroid Cancer (PTC). Objectives of this study are to investigate

Alpinumisoflavone exhibits anticancer activities in glioblastoma multiforme by suppressing glycolysis.

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Glioblastoma multiforme (GBM, WHO grade IV astrocytoma) has become a public health burden worldwide. Alpinumisoflavone (AIF) is a flavonoid compound isolated from Derris eriocarpa. This study aims to examine the role of AIF in GBM. Our results showed that AIF could decrease the cell viability of

[Studies on flavonoids from Derris eriocarpa].

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Derris eriocarpa, a traditional Chinese medicine belonging to the family of Leguminosae, is widely distributed mainly over Yunnan, Guangxi and Guizhou of China. Modern pharmacological researches on this herb showed that it had extensive bioactivities, such as promoting urination, removing dampness
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