ameloblastoma/protease

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StraipsniaiKlinikiniai tyrimaiPatentai

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Evaluation of neoplastic nature of keratocystic odontogenic tumor versus ameloblastoma.

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OBJECTIVE Although most of odontogenic tumors are benign, some of them will show locally destructive behavior, as keratocystic odontogenic tumor (KCOT) is now known as a benign but aggressive odontogenic neoplasm. The neoplastic characteristics in KCOT have been suggested from clinical as well as

Detection of mitochondria-mediated apoptosis signaling molecules in ameloblastomas.

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BACKGROUND To investigate the roles of the apoptosis signaling pathway mediated by mitochondria in oncogenesis and cytodifferentiation of odontogenic tumors, expression of pathway signaling molecules was analyzed in ameloblastomas as well as in tooth germs. METHODS Tissue specimens of 12 tooth

Role of immunomarkers in the clinicopathological analysis of unicystic ameloblastoma.

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OBJECTIVE The clinical behavior of unicystic ameloblastoma varies according to its subtype. The assessment of its proliferative capacity, neovascularization, and invasiveness using relevant immunomarkers may aid in appropriate surgical therapeutic protocol. METHODS 18 cases of clinically and

Expression of metallothionein in ameloblastoma. A regulatory molecule?

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BACKGROUND Ameloblastoma is a benign odontogenic tumor, exhibiting local invasiveness and high rate of recurrence. Metallothionein is a protein associated with tumorigenesis, serving as prognostic factor in different neoplasms. We are interested in mechanisms underlying ameloblastoma local

Immunohistochemical detection and distribution of enamelysin (MMP-20) in human odontogenic tumors.

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Enamelysin is a tooth-specific protease that was initially isolated from porcine enamel organ and subsequently from human odontoblasts. Since this protease is thought to play important roles in tooth development, the evaluation of enamelysin in odontogenic tumors may aid our understanding of the

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