digitoxin/kraujavimas

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[Haemorrhagic necrosis of the digestive tract consecutive to massive digitalis intoxication (author's transl)].

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A 60-year-old man under digitalis treatment for hypertensive heart tried to commit suicide by absorbing a 15 mg dose of digitoxin. Severe intestinal bleeding occurred 12 hours later, followed by pseudo-occlusive syndrome and ischaemia of the distal lower limbs. On abdominal incision the whole gut

[Thrombocytopenia in digitoxin poisoning].

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Because she felt unwell, an 80-year-old woman who was receiving treatment with digitoxin (0.07 mg daily) raised the dose on her own initiative to twice or three times the previous level. She then experienced faintness, visual abnormalities and bradyarrhythmia (rate about 40/min). The ECG showed 2

[Sex, erectile dysfunction, and the heart: a growing problem].

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BACKGROUND Erectile dysfunction (ED) is defined as the inability to attain and/or maintain penile erection sufficient for satisfactory sexual performance. ED may also be an early sign of cardiovascular disease. The main risk factors for coronary heart disease (high LDL, smoking, hypertension,

Prolonged anticoagulant activity of rivaroxaban in a polymorbid elderly female with non-convulsive epileptic state.

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OBJECTIVE Rivaroxaban, an oral direct factor Xa-inhibitor was non-inferior to adjusted dose warfarin in the prevention of stroke and embolism among patients with atrial fibrillation (AF) in the ROCKET-AF trial and has been approved for stroke prevention in AF. METHODS A 88-years-old female

Admissions caused by adverse drug events to internal medicine and emergency departments in hospitals: a longitudinal population-based study.

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OBJECTIVE To estimate incidence rates of drug-related hospitalizations (DRHs) in a longitudinal population-based study with prospective event assessment. METHODS Cohort study and time-trend analysis. METHODS All departments of internal medicine and emergency departments in the urban regions of Jena

Combinatorial screening of a panel of FDA-approved drugs identifies several candidates with anti-Ebola activities.

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Ebola virus (EBOV), pathogen of Ebola hemorrhagic fever (EHF), is an enveloped filamental RNA virus. Recently, the EHF crisis occurred in the Democratic Republic of the Congo again highlights the urgency for its clinical treatments. However, no Food and Drug Administration (FDA)-approved

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