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ellipticine/vėžys
Nuoroda įrašoma į mainų sritį
7 rezultatus
9-Hydroxy ellipticine
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Prisijungti Registracija
The present invention relates to a new product, 9-hydroxy ellipticine, or 9-hydroxy-5,11-dimethyl-(6H) pyrido [4,3-b] carbazole and a process for obtaining same. The invention further relates to the application of said compound as a medicament or as the active principle of pharmaceutical
2-N Quaternary ammonium salt derivatives of 9-hydroxy ellipticine
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Prisijungti Registracija
This invention relates to new products, namely 2-N-quaternized derivatives of 9-hydroxy-ellipticine, i.e. 2-N-quaternized derivatives of 9-hydroxy-5,11-dimethyl-(6H) pyrido[4,3-b]carbazole, and methods for obtaining same. The invention further relates to the application of said compounds as a
Ellipticine compounds
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Prisijungti Registracija
The present invention relates to new ellipticine compounds and to pharmaceutical compositions containing them. The compounds of the present invention have a valuable therapeutic use by virtue of their anti-tumour activity.
Some ellipticine compounds are already known for their anti-cancer
Ellipticine compounds
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Prisijungti Registracija
The present invention relates to new olivacine or ellipticine compounds, to a process for their preparation and to pharmaceutical compositions containing them.
The compounds of the present invention are used in therapeutics by virtue of their anti-tumour activity.
A number of compounds of the
Synthesis of pyrido[4,3-b]carbazole derivatives
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Prisijungti Registracija
This invention relates to new products, namely 2-N-quaternized derivatives of 9-hydroxy-ellipticine, i.e. 2-N-quaternized derivatives of 9-hydroxy-5,11-dimethyl-(6H) pyrido[4,3-b]carbazole, and methods for obtaining same. The invention further relates to the application of said compounds as a
Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
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Prisijungti Registracija
FIELD OF THE INVENTION
The present invention concerns covalent conjugates of topoisomerase I inhibitors (e.g., camptothecins) and topoisomerase II inhibitors (e.g., amsacrine, ellipticines, anthracycline antibiotics, epipodophyllotoxins).
BACKGROUND OF THE INVENTION
Etoposide is a widely-used
Taxoid conjugates as antimitotic and antitumor agents
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Prisijungti Registracija
FIELD OF THE INVENTION
The present invention concerns taxoid conjugates, pharmaceutical formulations containing the same, and methods of use thereof as antimitotic and antitumor agents, particularly for the treatment of tumors such as breast cancer and ovarian cancer.
BACKGROUND OF THE INVENTION
The
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