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fagaramide/zanthoxylum

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StraipsniaiKlinikiniai tyrimaiPatentai
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In our continuous search for cytotoxic compounds from the genus Zanthoxylum, chromatographic separation of the MeOH/CH2Cl2 (1:1) extract of Z. chalybeum yielded one new alkamide; 4-(isoprenyloxy)-3-methoxy-3,4-deoxymethylenedioxyfagaramide (1) and a known one; fagaramide (2).

α-Amylase and α-glucosidase inhibitors from Zanthoxylum chalybeum Engl. root bark

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A systematic analysis of the root bark of Zanthoxylum chalybeum was conducted to establish the antidiabetic potential of isolated compounds based on its ethnomedicinal use to manage diabetes. Chromatographic separation of alkaloid extracts led to isolation of three undescribed amides, chaylbemide A

Leaf Alkaloids of Zanthoxylum rubescens.

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An alkaloid, 8-methoxy dictamnine ( 1) and a fagaramide like compound ( 2) were isolated from the leaves of ZANTHOXYLUM RUBESCENS for the first time. These compounds were absent in the root and stem barks from which nitidine chloride (0.013% (w)/ (w))( 3) and 9-methoxylchelerythrine (0.18% (w)/

A Contribution to the Phytochemistry of Zanthoxylum tessmannii1.

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Root bark extracts of ZANTHOXYLUM TESSMANNII (Engl.) Ayafor COMB. NOV. (Syn. FAGARA TESSMANNII Engl.) yielded, besides chelerythrine, dihydrochelerythrine, fagaramide and lupeol previously reported from this taxon, ten other compounds viz:nitidine, dihydronitidine, 9-methoxychelerthrine,

Antiplasmodial activity and phytochemical analysis of extracts from selected Ugandan medicinal plants.

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BACKGROUND Resistance of the parasites to known antimalarial drugs has provided the necessity to find new drugs from natural products against malaria. The aim of the study was to evaluate the in vitro antiplasmodial activity of some plants used by Traditional Medical Practitioners (TMPs) of Prometra
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