glutamate oxalacetate transaminase/nekrozė

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Comparison of effects of paraquat and methidation on enzyme activity and tissue necrosis of carp, following exposure to the pesticides singly or in combination.

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Under aquarium conditions, treatment with the herbicide paraquat (PQ) and with the insecticide methidation (MD) caused cell damage and stress in carp (Cyprinus carpio L.), as shown by increases in glutamate-dehydrogenase (GIDH, EC 1.4.1.2), glutamate-oxalacetate transaminase (GOT, EC 2.6.1.1) and

Metabolic, endocrine and haematological responses to intravenous E. coli endotoxin administration in 1-week-old calves.

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Responses to i.v. injected E. coli endotoxin (E), followed by saline infusion, as compared with saline infusion alone, were studied for 24 h in 1-week-old calves. After administration of E, respiratory rate (RR), heart rate (HR), rectal temperature (RT), serum iron, insulin, (I), cortisol and tumor

Hepatoprotective activity of Trichilia roka on carbon tetrachloride-induced liver damage in rats.

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Trichilia roka Chiov. (Meliaceae) is a tree widely distributed in tropical Africa. It has been used in Mali folk medicine for the treatment of various illnesses. A decoction of the roots is taken as a remedy for colds and pneumonia, and it is used as a diuretic and in hepatic disorders. We have

No response of pigeon liver to dimethylnitrosamine acute effects.

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No evidence for liver necrosis was observed at 24, 48 or 72 h after injection of dimethylnitrosamine (DMN) (70 mg/kg, i.p.) to pigeons. The assessment of possible liver necrosis was made by determination of isocitric dehydrogenase (ICD), glutamate oxalacetate transaminase (GOT) and glutamate

Influence of hyperthyroidism on lindane-induced hepatotoxicity in the rat.

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Parameters related to hepatic oxidative stress, cell injury, phagocytic activity, and liver histology were studied in control rats and in animals subjected to L-3,3',5-triiodothyronine (T3) and/or lindane administration. Hyperthyroidism elicited a calorigenic response and increased rates of hepatic

Changes in rat plasma-free fatty acid composition under oxidative stress induced by carbon tetrachloride: decrease of polyunsaturated fatty acids and increase of palmitoleic acid.

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In order to measure the changes in antioxidant levels and the composition of plasma-free fatty acids resulting from oxidative stress, male Fisher rats were given a twice weekly subcutaneous injection of a 50% solution of carbon tetrachloride (CCl4) in corn oil for a period of 2 to 13 weeks. The

Role of nitric oxide in the circulatory failure and organ injury in a rodent model of gram-positive shock.

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1. The pathological features of Gram-positive shock can be mimicked by the co-administration of two cell wall components of Staphylococcus aureus, namely lipoteichoic acid (LTA) and peptidoglycan (PepG). This is associated with the expression of the inducible isoform of nitric oxide synthase (iNOS)

Anti-inflammatory effects of LK-3, on LPS-induced sepsis in rats.

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Dextromethorphan (DM), an antitussive agent, has been shown to have anti-inflammatory and immunomodulatory effects in vitro. Thus, the aim of this study was to evaluate the effects of LK-3, an analog of DM, on sepsis induced by intravenous (i.v.) administration of lipopolysaccharide (LPS; 10 mg/ kg)

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