gnidimacrin/vėžys

Nuoroda įrašoma į mainų sritį

Pasirinkite rūšiavimo tipą

8 rezultatus

[The antitumor activities of gnidimacrin isolated from Stellera chamaejasme L].

Straipsnius versti gali tik registruoti vartotojai

Prisijungti Registracija

Gnidimacrin, a diterpene compound, isolated from the methanol extract of Stellera chamaejasme L, showed significant antitumor activities against mouse leukemia P-388 and L-1210 in vivo. At the dosages of 0.02-0.03mg/kg ip, the in increase in life span (ILS) was 70% and 80%, respectively. Gnidimacrin

Involvement of PKC betaII in anti-proliferating action of a new antitumor compound gnidimacrin.

Straipsnius versti gali tik registruoti vartotojai

Prisijungti Registracija

Daphnane-type diterpene gnidimacrin (NSC 252940) shows significant antitumor activity against murine tumors and human tumor cell lines. This compound binds to and directly activates protein kinase C (PKC), arresting the cell cycle at the G(1) phase through inhibition of cdk2 activity in human K562

Overcoming drug resistance in lung cancer.

Straipsnius versti gali tik registruoti vartotojai

Prisijungti Registracija

Anticancer drugs have been explored by means of random screening and demonstrated to be active against not only hematologic malignancies but also some solid tumors. Recent progress in the field of molecular biology has identified many new molecular targets for anticancer drugs. In this review, for

Antitumor activity of daphnane-type diterpene gnidimacrin isolated from Stellera chamaejasme L.

Straipsnius versti gali tik registruoti vartotojai

Prisijungti Registracija

The daphnane-type diterpene gnidimacrin, isolated from the root of the Chinese plant, Stellera chamaejasme L., was found to strongly inhibit cell growth of human leukemias, stomach cancers and non-small cell lung cancers in vitro at concentrations of 10(-9) to 10(-10) M. On the other hand, even at

Antitumor action of the PKC activator gnidimacrin through cdk2 inhibition.

Straipsnius versti gali tik registruoti vartotojai

Prisijungti Registracija

Daphnane-type diterpene gnidimacrin (NSC252940), isolated from a Chinese plant, exhibited antitumor activity against murine leukemias and solid tumors. At concentrations of 10(-9) to 10(-10) M, this agent strongly inhibited the growth of human tumor cell lines. In sensitive human leukemia K562

Picomolar dichotomous activity of gnidimacrin against HIV-1.

Straipsnius versti gali tik registruoti vartotojai

Prisijungti Registracija

Highly active antiretroviral therapy (HAART) has offered a promising approach for controlling HIV-1 replication in infected individuals. However, with HARRT, HIV-1 is suppressed rather than eradicated due to persistence of HIV-1 in latent viral reservoirs. Thus, purging the virus from latent

alpha-Tocopherol inhibits 12-O-tetradecanoyl-phorbol-13-acetate-stimulated deacylation of cellular lipids, prostaglandin production, and changes in cell morphology of Madin-Darby canine kidney cells.

Straipsnius versti gali tik registruoti vartotojai

Prisijungti Registracija

Incubation of the tumor-promoting phorbol diester, 12-O-tetradecanoyl-phorbol-13-acetate with Madin-Darby canine kidney cells (MDCK) stimulated deacylation of phospholipids, prostaglandin production and altered cell morphology. alpha-Tocopherol, if present during the incubation, inhibited these

Neuroprotective versus tumorigenic protein kinase C activators.

Straipsnius versti gali tik registruoti vartotojai

Prisijungti Registracija

Protein kinase C (PKC) activators possess potent neurotrophic and neuroprotective activity, thus indicating potential applications in treating neurodegenerative diseases, stroke and traumatic brain injury. Although some activators, such as bryostatin and gnidimacrin, have been tested as antitumor

Prisijunkite prie mūsų
„Facebook“ puslapio

Herbal & Natural Medicine

Išsamiausia vaistinių žolelių duomenų bazė, paremta mokslu

Dirba 55 kalbomis
Žolelių gydymas, paremtas mokslu
Vaistažolių atpažinimas pagal vaizdą
Interaktyvus GPS žemėlapis - pažymėkite vaistažoles vietoje (netrukus)
Skaitykite mokslines publikacijas, susijusias su jūsų paieška
Ieškokite vaistinių žolelių pagal jų poveikį
Susitvarkykite savo interesus ir sekite naujienas, klinikinius tyrimus ir patentus

Įveskite simptomą ar ligą ir perskaitykite apie žoleles, kurios gali padėti, įveskite žolę ir pamatykite ligas bei simptomus, nuo kurių ji naudojama.
* Visa informacija pagrįsta paskelbtais moksliniais tyrimais