A device includes a handle coupled with an activated textured surface that can be implemented using a repetitive movement mechanism and a treatment energy source, such as an electromagnetic radiation source. The handle may be used to provide detection, treatment and/or management of sundry conditions including, for example, tooth discoloration, tissue damage, periodontal disease, tumors, pain, halitosis, and bronchitis. The activated textured surface may include a surface topography including corrugations, bristles, protuberances, or pits, or other surfaces for facilitating agitation, cleaning or other surface treatments.

Biolase Technology, Inc.

Electromagnetic radiation emitting toothbrush and dentifrice system

The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compounds--Free-B-Ring flavonoids and flavans--for use in the prevention and treatment of diseases and conditions associated with mouth, gums and teeth. This composition of matter simultaneously inhibits cyclooxygenase (COX) and lipoxygenase (LOX) enzymatic activity and reduces cytokine production at the mRNA level in normal, aged and damaged periodontal cells and tissues. This invention further provides a method for the prevention and treatment of diseases and conditions of the mouth, gums and teeth. The method for preventing and treating diseases and conditions of the mouth, teeth and gums is comprised of administering to a host in need thereof a therapeutically effective amount of a composition comprising a mixture of Free-B-Ring flavonoids and flavans synthesized and/or isolated from a single plant or multiple plants, preferably in the Scutellaria, Oroxylum, Acacia or Uncaria genus of plants and pharmaceutically and/or cosmetically acceptable carriers. Finally the present invention provides a method for the prevention and treatment of diseases and conditions of the mouth, teeth or gums, including but not limited to periodontal diseases, such as gingivitis, periodontitis, pulpitis, periodontal conditions caused by the physical implantation of oral dentures, trauma, injuries, bruxism, neoplastic and other degenerative processes; material alba, pellicles, dental plagues, calculus, and stains. Use of the composition described herein also affords the benefit of maintaining optimum saliva production and pH, minimizing bacterial growth, reducing the formation of pellicles and plague, inhibiting tooth decalcification and tooth caries (decay), promoting remineralization, which yields healthy gums, whitening teeth, maintaining healthy oral hygiene and reducing oral malodor (halitosis).

Jia; Qi

Zhao; Yuan

halitosis/vėžys

Electromagnetic radiation emitting toothbrush and dentifrice system

Electromagnetic radiation emitting toothbrush and dentifrice system

Formulation of dual eicosanoid system and cytokine system inhibitors for use in the prevention and treatment of oral diseases and conditions

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