hemoglobinopathies/kalis

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Potassium tolerance in sickle-cell hemoglobinopathy.

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Hyperkalemic hyperchloremic metabolic acidosis in sickle cell hemoglobinopathies.

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This report describes the occurrence of hyperkalemic hyperchloremic metabolic acidosis in six patients with sickle cell hemoglobinopathies. Three patients had sickle cell anemia, two had sickle cell trait and one had S-C disease. In all patients, decreased renal potassium excretion was demonstrated

Human pythiosis associated with thalassemia hemoglobinopathy syndrome.

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Pythium infection (pythiosis) in humans has not previously been described, even in areas endemic for animal pythiosis. We report five patients with a unique presentation of fungal arteritis. The medium- to large-sized arteries were involved, and in some cases this involvement led to gangrene of the

Compliance with penicillin prophylaxis in patients with sickle cell disease.

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OBJECTIVE To assess factors related to compliance with penicillin prophylaxis among patients with sickle cell disease. METHODS Prospective case series. METHODS Urban pediatric medical center where universal penicillin prophylaxis is recommended for all patients with any sickle cell hemoglobinopathy

Laboratory exams of the National Health Survey: methodology of sampling, data collection and analysis.

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This article aims at describing the National Health Survey (Pesquisa Nacional de Saúde- PNS) methodology of collecting laboratory exams data.A subsample of 25% of the census tracts was selected, according to the stratification of the PNS sample, with a

Renal abnormalities in sickle cell disease.

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Sickle cell anemia and the related hemoglobinopathies are associated with a large spectrum of renal abnormalities. The patients have impaired urinary concentrating ability, defects in urinary acidification and potassium excretion, and supranormal proximal tubular function. The latter is manifest by

Vascular pythiosis in a thalassemic patient.

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Pythium insidiosum is a fungus that causes disease in both animals and humans. Human pythiosis is an emerging disease in the tropical, subtropical, and temperate regions of the world, occurring in localized and systemic or vascular forms. Most patients with arterial pythiosis have an underlying

Prophylaxis with oral penicillin in children with sickle cell anemia. A randomized trial.

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Children with sickle cell anemia have an increased susceptibility to bacterial infections, especially to those caused by Streptococcus pneumoniae. We therefore conducted a multicenter, randomized, double-blind, placebo-controlled clinical trial to test whether the regular, daily administration of

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