Puslapis 1 nuo 626 rezultatus
•A drug-resistant epilepsy case showed hypermotor seizures and amygdala enlargement.•Seizure onset zone was the hippocampus, not amygdala, as revealed by SEEG.•The enlarged amygdala pathology was classified as FCD type I.•Selective amygdalohippocampectomy led to good outcomes.
The association between emotional stimuli and temporal lobe epilepsy (TLE) is largely unknown. Here, we report the case of a depressed, 50-year-old female complaining of episodes of a "spaced out" experience precipitated by emotional stimuli. Psychogenic non-epileptic attacks were suspected.
Hypertrophic cardiomyopathy is a newly recognized, potentially fatal complication of ACTH therapy. We report the clinical, echocardiographic, and pathologic findings of an infant who was treated with ACTH for seizure disorder and subsequently developed severe systemic hypertension. Echocardiography
Rats treated with the NMDA-blocker, ketamine hydrochloride 30 minutes after the induction of seizures by lithium/pilocarpine exhibited statistically smaller lateral ventricles in the left hemisphere compared to rats that had received acepromazine after the induction of these seizures. In addition,
Rats treated with the NMDA-blocker, ketamine hydrochloride 30 minutes after the induction of seizures by lithium pilocarpine exhibited statistically smaller lateral ventricles in the left hemisphere compared to rats that had received acepromazine after the induction of these seizures. In addition,
OBJECTIVE
Amygdala enlargement (AE) has been suggested to be a subtype of mesial temporal lobe epilepsy (MTLE). However, most reports related to AE have referred to imaging studies, and there have been few reports regarding surgical and pathological findings. The present study was performed to
The white matter of resected temporal lobes from patients with intractable complex partial seizures shows increased cellularity which appears to be related to glia and neurons. This study, using quantitative methods, defines an increase in glial cell numbers and a significant increase in glial
Malformations of the cerebral cortex known as cortical dysplasia account for the majority of cases of intractable childhood epilepsy. With the exception of the tuberous sclerosis complex, the molecular basis of most types of cortical dysplasia is completely unknown. Currently, there are no good
Non-specific X-linked mental retardation is a heterogeneous group of disorders with an incidence of approximately 1 in 500 males. A recently identified gene in Xq12, encoding a Rho-GTPase-activating protein, was found to be mutated in individuals with mental retardation. We describe here two sisters
Limbic seizures induce in vulnerable structures, such as the hippocampal complex, morphologic changes that may contribute to the development of epilepsy. They include neuronal cell death, reactive gliosis, and neosynapse formation. In temporal lobe epilepsy patients, cell death develops in Ammon's
Phacomatosis pigmentokeratotica (PP) is a mosaic disorder that represents a distinct epidermal naevus syndrome. Its defining features are an epidermal naevus that is usually of the sebaceous type and a speckled lentiginous naevus arranged in a chequerboard pattern. In addition, there are
We report a case of acute enlargement of the ventricles within 7 hours after head injury that was documented by repeated computerized tomography. It is suggested that the pathophysiological mechanism for this rapid enlargement of ventricles may be due to the raised intracranial pressure (ICP) that
Affective disorders are commonly associated with epilepsy. Affective symptoms rarely occur concomitantly with seizure occurrence, which can lead to misdiagnosis. Here, we describe a 69-year-old man who experiencedintermittent manifestations of unpleasant mood and aggressive behavior. He had temporal
The usefulness of ACTH in the treatment of childhood epilepsy is assessed by improvement in the EEG and in the clinical condition. However, pronounced side effects, even serious ones, must be encountered. The most common complications are Cushing syndrome, infections, and arterial hypertension. We