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6 rezultatus
Electrosclerotherapy for Capillary Malformations
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Prisijungti Registracija
Capillary malformations are congenital abnormalities of the capillaries in the skin. These abnormally developed blood vessels cause a red color of the skin (also known as 'port-wine stain'),often in combination with a cobble-stone like aspect of the skin. Currently, the only widely accepted
Calibrating Imaging Techniques to Study Blood Flow
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Prisijungti Registracija
This study is designed to calibrate three non-invasive and non-ionizing imaging techniques on 12 healthy volunteers. The three imaging techniques-- thermography, laser Doppler imaging and multi-spectral imaging-- have been approved since 2001 for four clinical protocols already approved by the
Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With Advanced Solid Tumors.
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Prisijungti Registracija
Despite constant progress in the treatment of patients with advanced solid tumors failing standard systemic treatment, there is still a high unmet medical need to develop new active anticancer drugs or therapies. Although patients with advanced melanoma have benefitted substantially from the new
Childhood Cancer and Plexiform Neurofibroma Tissue Microarray for Molecular Target Screening and Clinical Drug Development
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Prisijungti Registracija
Background: Cancer drug discovery is now focused on identifying molecularly targeted drugs that are more selective and specific for proteins and signaling pathways that are directly involved in tumorigenesis. This new paradigm alters the approach to clinical drug development for childhood cancers
Depsipeptide/Flavopiridol Infusion for Cancers of the Lungs, Esophagus, Pleura, Thymus or Mediastinum
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Prisijungti Registracija
Background:
In preclinical studies we have demonstrated that the histone deacetylase (HDAC) inhibitor Depsipeptide FR901228 (DP) mediates cell cycle arrest and apoptosis in cultured lung and esophageal cancer, and malignant pleural mesothelioma cells.
We have observed that the cdk inhibitor
Changes in Biomarkers From Blood Over Time in Patients With Pancreatic Adenocarcinoma
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Prisijungti Registracija
This is a single-institutional, prospective study at the Johns Hopkins Hospital which will be conducted from January 1, 2015 to December 31, 2018. All patients who present to the Johns Hopkins Hospital with a pancreatic adenocarcinoma (PDAC) for evaluation of treatment by chemotherapy, radiation
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