miyabenol c/karagana

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Oligomeric stilbenes from the root of Caragana stenophylla.

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Caragaphenol A (1), a new trimeric stilbene, was isolated from the roots of Caragana stenophylla (Leguminosae) along with three known oligomeric stilbenes: (+)-alpha-viniferin (2), miyabenol C (3) and kobophenol A (4). The stereostructure of 1 was elucidated by one- and two-dimensional (1D- and

Antioxidative oligostilbenes from Caragana sinica.

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Two new oligostilbenes, caragasinins A (5) and B (10), and eight known compounds, kobophenol A (1), (+)-α-viniferin (2), (+)-ampelopsin F (3), pallidol (4), (+)-isoampelopsin F (6), miyabenol C (7), carasinaurone (8) and caraphenol B (9) were isolated from the ethylacetate-soluble extract of the

Determination of hypaphorine and oligomeric stilbenes in the root of Caragana sinica by capillary electrophoresis with electrochemical detection.

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Capillary electrophoresis with electrochemical detection (CE-ED) was employed for the determination of hypaphorine (an alkaloid) and four oligomeric stilbenes (including pallidol, kobophenol A, miyabenol C and (+)-alpha-viniferin) in Radix seu Cortex Caraganae Sinicae, the root of Caragana sinica

Stilbene derivatives as human 5-HT(6) receptor antagonists from the root of Caragana sinica.

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The 5-HT₆ receptor (5-HT₆R) is a member of the class of recently discovered 5-hydroxytryptamine (5-HT) receptors. Due to the lack of selective 5-HT₆R ligands, the cellular signaling mechanisms of the 5-HT₆R are poorly understood. We previously developed a cell-based high-throughput screening (HTS)

Identification and determination of oligomeric stilbenes in the roots of Caragana species by capillary electrophoresis.

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A method based on capillary electrophoresis with electrochemical detection (CE-ED) was employed for the determination of one alkaloid (hypaphorine) and the four oligomeric stilbenes, pallidol, kobophenol A, miyabenol C and (+)-alpha-viniferin in the roots of Caragana species. The five analytes could

Naturally occurring protein kinase C inhibitors; II. Isolation of oligomeric stilbenes from Caragana sinica.

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The oligomeric stilbenes (+)-alpha-viniferin (1), miyabenol C (2), and kobophenol A (3) have been isolated from Caragana sinica (Buchoz) Rehd (Leguminosae). (+)-alpha-Viniferin (1) and miyabenol C (2) exhibited protein kinase C inhibitory activity at low micromolar concentrations.

[Inhibition of protein kinase C by stilbenoids].

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The effect of 15 stilbenoids on protein kinase C (PKC) was studied in order to search for naturally occurring PKC inhibitors. All these compounds were isolated from Chinese medicines. Three oligomeric stilbenes from Caragana sinica, alpha-viniferin, kobophenol A and miyabenol C, were shown to

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