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High anti-inflammatory activity of harpagoside-enriched extracts obtained from solvent-modified super- and subcritical carbon dioxide extractions of the roots of Harpagophytum procumbens.

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Solvent-modified carbon dioxide extractions of the roots of Harpagophytum procumbens have been investigated with respect to extraction efficiency and content of harpagoside, and compared with a conventional extract. The effects of pressure, temperature, type and concentration of the modifier have

[Cutaneous protothecosis: first case in Taiwan].

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In November 1985, a 5-year-old Chinese girl presented to the Dermatological Department of Chang Gung Memorial Hospital, Taipei, having scaly erythematous plaque with mild itching on her right upper eyelid. Skin biopsy and fungal cultures were performed after failure of initial topical steroid

Purification and analysis of a phospholipase A2-like lytic factor of Trichomonas vaginalis.

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Trichomonas vaginalis produces soluble factors that have been reported to have the ability to damage target cells in vitro, and it has been hypothesized that these factors may play a role in the pathogenesis of human trichomoniasis. A lytic factor (LF) was purified from T. vaginalis, and the

Comparison of drug binding sites on rat and human serum albumins using immobilized-protein stationary phases as a tool for the selection of suitable animal models in pharmacological studies.

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Immobilized serum albumins (rat and human) HPLC stationary phases have been used to investigate and to compare the binding sites of a number of analytes of pharmaceutical interest assessing the retention time as the chromatographic parameter which correlates the percentage of drug-binding of the

Specific barrier response profiles after experimentally induced skin irritation in vivo.

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BACKGROUND Recently, natural moisturizing factors (NMFs) and corneocyte surface topography were suggested as biomarkers for irritant dermatitis. OBJECTIVE To investigate how exposure to different irritants influences corneocyte surface topography, NMF levels and the barrier function of human skin in

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