ocular hypertension/edema

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Straipsniai Klinikiniai tyrimai Patentai

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Safety of Topical Insulin Drops for Open-angle Glaucoma

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Glaucoma: a major health care challenge of the 21st century Glaucoma is a leading cause of irreversible blindness worldwide and is expected to affect 76 million people by the year 2020. In glaucoma, there is a permanent loss of retinal ganglion cells (RGCs), the long-projecting central nervous

Combination OZURDEX® & EyLea® vs. OZURDEX® Monotherapy in IncompLete-Responders wIth Diabetic Macular Edema

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Diabetic macular edema (DME) is a common cause of vision loss in patients with diabetes. The pathophysiology of DME is complex and likely multifactorial, where some of the most important features include the accumulation of advanced glycation end products, reactive oxygen species, protein kinase C

Efficacy and Safety of Lens Extraction in Patients With Pseudoexfoliation Glaucoma

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INTRODUCTION Pseudoexfoliation (PXF) is a pathology characterized by the accumulation of extracellular microfibrillar material in the anterior segment of the eye. It was first described by Lindberg in Finland in 1917 and is the most common identifiable cause of glaucoma. It is diagnosed clinically

Safety, Tolerability and Preliminary Efficacy of Unilateral Latanoprost-loaded Punctual Plug -EXP-LP

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Device Description - A combination of punctual plug (new product) as delivery system for Latanoprost (already approved drug). The plug has 2 different sizes of "big plug" (450 µg API) and "small plug" (250 µg API) (Neck diameter of 1.08 mm and 1.06 mm, accordingly) EXP-LP punctum plug is intended to

Bevacizumabe or Triamcinolone for Persistent Diabetic Macular Edema

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Methods Study Design. The current study is a prospective randomized clinical trial registered at ClinicalTrials.gov (NCT02985619). The study protocol adhered to the tenets of the Declaration of Helsinki and was approved by the local Institutional Review Board, research ethics committee of School of

Prophylaxis for Anti-VEGF-induced IOP Elevation

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The recent introduction of antivascular endothelial growth factor (anti-VEGF) agents has quickly progressed to become the standard of care for several ocular diseases. Between 2006 and 2010, anti-VEGF treatment for neovascular age-related macular degeneration (AMD) was initiated in over 620 000 eyes

Bevacizumab Versus Ranibizumab for Diabetic Retinopathy

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Efficacy and Safety Study of Intravitreal Triamcinolone to Treat Diffuse Diabetic Macular Edema

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Diabetes mellitus and its complications represent nowadays an important issue in Public Health terms. The WHO expectations indicate that around 2025 the European population with diabetes will reach about 12%, and it has been estimated that the percent in the USA will be around 10% (King, 1995). The

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