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panic disorder/seizures
Nuoroda įrašoma į mainų sritį
9 rezultatus
Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels
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BACKGROUND OF THE INVENTION
Lennox-Gastaut Syndrome (LGS) is a severe pediatric epilepsy disorder associated with various types of seizures and cognitive dysfunction that persist into adulthood. As a result, LGS patients suffer from varying degrees of learning disabilities, psychiatric disorders,
Rufinamide and derivatives and their use in modulating the gating process of human voltage-gated sodium channels
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BACKGROUND OF THE INVENTION
Lennox-Gastaut Syndrome (LGS) is a severe pediatric epilepsy disorder associated with various types of seizures and cognitive dysfunction that persist into adulthood. As a result, LGS patients suffer from varying degrees of learning disabilities, psychiatric disorders,
Ethinyl-pyrazole derivative
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a National Stage of International Application No. PCT/JP2011/067394 filed Jul. 29, 2011, claiming priority based on Japanese Patent Application No. 2010-170732 filed Jul. 29, 2010, the contents of all of which are incorporated herein by
7-piperidinoalkyl-3, 4-Dihydroquinolone derivative
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CROSS REFERENCE TO RELATED APPLICATIONS
This is a National Stage of International Application No. PCT/JP2009/067441 filed Sep. 30, 2009, claiming priority based on Japanese Patent Application No. 2008-257072 filed Oct. 2, 2008, the contents of all of which are incorporated herein by reference in
Deuterium-enriched alkyl sulfonamides and uses thereof
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FIELD OF THE INVENTION
The present invention generally relates to deuterium-enriched N-acetylamino-(piperazinyl)-butyl)-alkylsulfonamides of formula 1, their pharmaceutically acceptable salts, synthesis and methods of use thereof. These compounds are 5-HT (serotonin) receptor modulators more
Piperazinyl-propyl-pyrazole derivatives as dopamine D4 receptor antagonists, and pharmaceutical compositions containing the same
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CROSS REFERENCE TO RELATED APPLICATION
This application claims the priority of Korean Patent Application No. 10-2007-0022845, filed on Mar. 8, 2007 in the KIPO (Korean Intellectual Property Office), the disclosure of which are incorporated herein in their entirety by reference. Further, this
Piperazinyl-propyl-pyrazole derivatives as dopamine D4 receptor antagonists, and pharmaceutical compositions containing the same
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TECHNICAL FIELD
The present invention relates to a piperazinyl-propyl-pyrazole derivative, a method of its preparation and a pharmaceutically acceptable salt comprising the same.
BACKGROUND ART
Dopamine is a neurotransmitter essential for neuronal signal transduction in animal brains including
Tryptamine sulfonamides as 5-HT.sub.6 antagonists
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BACKGROUND OF THE INVENTION
Serotonin (5-hydroxy-tryptamine) (5-HT) receptors play an important role in many physiological and pathological functions like anxiety, sleep regulation, aggression, feeding and depression. The 5-HT receptors are distributed throughout the body and can be divided is into
Method for treatment of recurrent paroxysmal neuropsychiatric
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This invention relates to methods for the treatment of recurrent paroxysmal neuropsychiatric disorders of rapid onset and brief duration, such as acute dystonic reactions, seizure disorder and panic disorder.
Acute Dystonic Reactions are a common, frightening, extremely uncomfortable and potentially
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