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physostigmine/fatigue
Nuoroda įrašoma į mainų sritį
5 rezultatus
Intracerebroventricular physostigmine facilitates heat loss mechanisms in running rats.
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The aim of this study was to evaluate the participation of central cholinergic transmission in the regulation of metabolic rate, core temperature, and heat storage in untrained rats submitted to exercise on a treadmill (20 m/min, 5% inclination) until fatigue. The animals were separated into eight
Heat loss during exercise is related to serotonin activity in the preoptic area.
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To investigate the influence of the central cholinergic system on thermoregulation and brain serotonin concentration during exercise; 2 microl of physostigmine (5x10 M) or saline solution was injected into the lateral cerebral ventricle of running rats. At fatigue, brains were quickly removed and
Muscarinic modulation of calcium dependent plateau potentials in rat neostriatal neurons.
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Intracellular recording from neostriatal neurons in rat brain slices revealed effects of the acetylcholine (ACh) agonist carbachol (Cch, 1-10 mumol/l), of the anticholinesterase physostigmine (10 mumol/l) and of the muscarinic antagonist atropine (10 mumol/l) on plateau potentials elicited in the
Chronic acetylcholinesterase overexpression induces multilevelled aberrations in mouse neuromuscular physiology.
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Chronic overexpression of the acetylcholine-hydrolysing enzyme acetylcholinesterase (AChE) is a notable consequence of exposure to anticholinesterase drugs or poisons. However, the physiological consequences for the resultant neuromuscular disfunction have not yet been carefully analysed. Here we
The dynamics of physical exercise-induced increases in thalamic and abdominal temperatures are modified by central cholinergic stimulation.
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Evidence has shown that brain and abdominal (T abd) temperatures are regulated by distinct physiological mechanisms. Thus, the present study examined whether central cholinergic stimulation would change the dynamics of exercise-induced increases in T abd and thalamic temperature (T thal), an index
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