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sea/priešvėžiniai vaistai
Nuoroda įrašoma į mainų sritį
8 rezultatus
Naamidine A extracted from sea sponges and methods for its use as an anti-tumor agent
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BACKGROUND
The research underlying the following technology was supported by NIH Grants CA 36622 and CA 50750.
1. Field of the Invention
This invention relates to the isolation of naamidine A from sea sponges and methods for its use as an inhibitor of tumor growth. In particular, the present
Antiviral and antitumor cyclohexadienone compositions
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FIELD OF THE INVENTION
This invention relates to new cyclohexadienone derivatives which have useful antiviral and antitumor activity. More particularly, this invention relates to cyclohexadienone derivatives with antiviral and antitumor activities which are derived from marine organisms, i.e. red
Antitumor chamigrene derivatives and their methods of use
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FIELD OF THE INVENTION
This invention relates to compositions comprising, as active ingredients chamigrene derivatives, which have newly discovered and useful biological activity. More particularly, this invention relates to pharmaceutical compositions comprising, as active ingredients, chamigrene
Peptides having anti-cancer and anti-inflammatory activity
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TECHNICAL FIELD
The present invention relates to the fields of cancer treatment, inflammatory disease, and peptide chemistry.
BACKGROUND
The amino acid sequence Leu-pro-pro-ser-arg (SEQ ID NO:1) is a known immunostimulant and is described in papers by W. Weigle and is the subject of a US Patent.
Cancer inhibitory peptides
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INTRODUCTION
This invention relates generally to the field of peptides useful in chemotherapy and more particularly to the elucidation and synthesis of selected peptides which are structurally related to dolastatin 10. More particularly, the present invention relates to the synthesis of seven
Human cancer inhibitory pentapeptide amides
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INTRODUCTION
This invention relates generally to the field of antineoplastic compounds and more particularly to the synthesis of pentapeptide amides exhibiting antineoplastic effects.
BACKGROUND OF THIS INVENTION
Ancient marine invertebrate species of the Phyla Bryozoa, Molluska, and Porifera have
Isolation and structural elucidation of the cytostatic linear depsipeptides dolastatin 13 and dehydrodolastatin 13
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INTRODUCTION
The present invention relates to cytostatic linear depsipeptides herein denominated "Dolastatin 13" and "Dehydrodolastatin 13" which are obtained from the Indian Ocean shell-less mollusk Dolabella auricularia; to pharmaceutical preparations containing Dolastatin 13 and Dehydrodolastatin
Elucidation and synthesis of selected pentapeptides
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This invention relates generally to the field of antineoplastic compounds, and more particularly to the elucidation and synthesis of selected pentapeptides prepared by coupling dipeptide salts with the known tripeptide-trifluoroacetate salt. More particularly, the present invention relates to the
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