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Puslapis 1 nuo 16 rezultatus
Inhibition of angiogenesis by sea cucumber fractions
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FIELD OF THE INVENTION
The present invention relates to compositions for inhibiting angiogenesis in warm-blooded animals. More particularly, the present invention relates to the inhibition of angiogenesis by administering distinct fractions of the echinoderm sea cucumber which comprise:
1. the
Naamidine A extracted from sea sponges and methods for its use as an anti-tumor agent
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BACKGROUND
The research underlying the following technology was supported by NIH Grants CA 36622 and CA 50750.
1. Field of the Invention
This invention relates to the isolation of naamidine A from sea sponges and methods for its use as an inhibitor of tumor growth. In particular, the present
Method for testing for the presence of metastatic tumor cells
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BACKGROUND OF THE INVENTION
(1) Field of the Invention
The present invention relates to a method for testing for the presence of metastatic human tumor cells by determining the level of Human Leukocyte Antigen (HLA) in the tumor cells. In particular the present invention relates to a method which
Human cancer inhibitory pentapeptide amides
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INTRODUCTION
This invention relates generally to the field of antineoplastic compounds and more particularly to the synthesis of pentapeptide amides exhibiting antineoplastic effects.
BACKGROUND OF THIS INVENTION
Ancient marine invertebrate species of the Phyla Bryozoa, Molluska, and Porifera have
Cancer inhibitory peptides
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INTRODUCTION
This invention relates generally to the field of peptides useful in chemotherapy and more particularly to the elucidation and synthesis of selected peptides which are structurally related to dolastatin 10. More particularly, the present invention relates to the synthesis of seven
Peptides having anti-cancer and anti-inflammatory activity
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TECHNICAL FIELD
The present invention relates to the fields of cancer treatment, inflammatory disease, and peptide chemistry.
BACKGROUND
The amino acid sequence Leu-pro-pro-ser-arg (SEQ ID NO:1) is a known immunostimulant and is described in papers by W. Weigle and is the subject of a US Patent.
Cell growth inhibitory substance
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INTRODUCTION
The present invention relates generally to cell growth inhibition and more particularly to a potent cell growth inhibitory substance herein denominated "Dolastatin 10" which is obtained from the Indian Ocean sea hare Dolabella, to pharmaceutical preparations containing Dolastatin 10 as
Synthesis of dolastatin 15
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BACKGROUND OF THE INVENTION
The rapidly intensifying search for biologically and medicinally important marine organism constituents has attracted a great deal of interest world-wide. Not unexpectedly, a reassuring number of marine animals, plants and microorganisms are being found to produce
Therapeutic method using fucose-containing proteoglycan or acidic glycan
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to a class of proteoglycans having fucosylated acidic glycan side chains bound to a protein backbone which have been found to stimulate selectively proliferation of natural killer (NK) cells and/or .gamma..delta.T cells.
Fucose containing proteoglycan or acidic glycan and their pharmaceutical use
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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
Not Applicable
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to a class of proteoglycans having fucosylated acidic glycan side chains bound to a protein backbone which have been found to stimulate
Fucose containing proteoglycan or acidic glycan and their pharmaceutical use
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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
Not Applicable
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to a class of proteoglycans having fucosylated acidic glycan side chains bound to a protein backbone which have been found to stimulate
Antiviral and antitumor cyclohexadienone compositions
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FIELD OF THE INVENTION
This invention relates to new cyclohexadienone derivatives which have useful antiviral and antitumor activity. More particularly, this invention relates to cyclohexadienone derivatives with antiviral and antitumor activities which are derived from marine organisms, i.e. red
Antitumor chamigrene derivatives and their methods of use
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FIELD OF THE INVENTION
This invention relates to compositions comprising, as active ingredients chamigrene derivatives, which have newly discovered and useful biological activity. More particularly, this invention relates to pharmaceutical compositions comprising, as active ingredients, chamigrene
Method of treating pain or itching with APETx2 peptide toxin
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CROSS-REFERENCE TO RELATED APPLICATION
This application is a National Stage entry of International Application No. PCT/FR2009/000657, filed Jun. 4, 2009, which claims priority to French Patent Application No. 08/03158 filed Jun. 6, 2008, the disclosure of the prior application is incorporated in its
Method for measuring blood procoagulant activity of human leukocyte antigens
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BACKGROUND OF THE INVENTION
(1) Field of the Invention
The present invention relates to a method for inhibiting blood procoagulant activity of a histocompatibility antigen ((HLA). In particular, the present invention relates to the use of an enterotoxin to inhibit the activity, particularly in
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