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sennoside a/cassia

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StraipsniaiKlinikiniai tyrimaiPatentai
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Senna is an important medicinal plant and is used in many Ayurvedic formulations. Dianthraquinone glucosides are the main bioactive phytochemicals present in leaves and pods of senna. The extraction efficiency in terms of yield and composition of the extract of senna prepared using both conventional

Liquid chromatographic determination of sennosides in Cassia angustifolia leaves.

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A simple liquid chromatographic method was developed for the determination of sennosides B and A in leaves of Cassia angustifolia. These compounds were extracted from leaves with a mixture of methanol-water (70 + 30, v/v) after defatting with hexane. Analyte separation and quantitation were achieved
In vitro protocol has been established for clonal propagation of Cassia angustifolia Vahl which is an important source of anticancerous bioactive compounds, sennoside A and B. Nodal explants excised from field raised elite plant (showing optimum level of sennoside A and B) of C. angustifolia when

A cosmetic senna, Cassia obovata: 'neutral henna'.

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Summary The powder made with leaflets of a senna, Cassia obovata Coll., is a cosmetic mis-called 'neutral henna' The traditional use of C. obovata is as a laxative. The principal active components of this laxative drug are sennosides A and B. In the Middle Ages the blend of henna (Lawsonia inermis)
Laxative effects of Senna preparations are mainly mediated by rheinanthrone, a metabolite formed in the intestinal flora from dianthrones. Nevertheless, it was not clear whether dianthrones are bioavailable at all and contribute to the overall effects of this important medicinal plant. Using the
Components that could be used as indicators for the discrimination of senna (Cassia angustifolia) from other cassia plants contained in health teas were identified, and an analytical method for the components was developed. Our results revealed two components in senna that were not found in other

Formation and distribution of sennosides in Cassia angustifolia, as determined by a sensitive and specific radioimmunoassay.

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A radioimmunoassay for the quantitation of nanogram-amounts of sennoside B and related compounds in plant extracts is described. The assay makes use of [ (3)H]-8-glucosidorheinanthrone of high specific activity (5.2 Ci/mmol) whose synthesis is reported here. From this material, [ (3)H]-sennoside A
Experiments were conducted to evaluate the promise of Tinnevelly senna, Cassia angustifolia Vahl, as an alternative crop for stressful agroecosystems. Effects of drought, foliar nitrogen application and crop type on sennoside yields were studied with simultaneous measurements of net photosynthesis.

[Isolation and structural definition of a new sennoside from Cassia senna L. (author's transl)].

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The optical isomer of sennoside A--called sennoside A1--postulated by Stoll already in 1950--was isolated from senna pods. Structure identification was carried out by TLC, HPLC, UV, CD and MS.

An improved method for the analysis of sennosides in Cassia angustifolia by high-performance liquid chromatography.

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A reversed-phase column liquid chromatographic method for the analysis of sennosides A and B present in leaf and pod extracts of Cassia angustifolia has been developed using a Symmetry C18 column and a linear binary gradient profile. The method can be utilised for the quantitative determination of
Senna leaf is widely consumed as tea to treat constipation or to aid in weight loss. Sennoside A, A1 , and B are dirheinanthrone glucosides that are abundant and the bioactive constituents in the plant. They are isomers that refer to the (R*R*), (S*S*), and (R*S*) forms of protons on C-10 and C-10'
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