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5 rezultatus
Extrapulmonary silicosis in two water buffaloes.
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Prisijungti Registracija
Two cases of extrathoracic silicosis in buffaloes raised near a quartz quarry and suffering from clinically severe silicosis are described. The extrapulmonary changes were characterized by silicoconiotic nodules in the tonsils, mesenteric lymph nodes and spleen. A combination of energy dispersive
Nicorandil ameliorates pulmonary inflammation and fibrosis in a rat model of silicosis.
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Prisijungti Registracija
Nicorandil, an antianginal and potassium channel opener agent, has different useful impacts on cardiovascular and respiratory systems. Its effect against silicosis has not been discussed yet, therefore, this is an attempt to decide whether nicorandil can reduce silica-induced lung injury in rats.
The Nalp3 inflammasome is essential for the development of silicosis.
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Prisijungti Registracija
Inhalation of crystalline silica and asbestos is known to cause the progressive pulmonary fibrotic disorders silicosis and asbestosis, respectively. Although alveolar macrophages are believed to initiate these inflammatory responses, the mechanism by which this occurs has been unclear. Here we show
Silicate pneumoconiosis of farm workers.
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Prisijungti Registracija
Abnormal numbers of birefringent particles have been found in the lungs of seven patients (five vineyard workers, one farmer, and one rural resident) in association with a spectrum of early to late interstitial inflammation and fibrosis. Nodular granulomas of the type seen in silicosis were absent.
PolyG mitigates silica-induced pulmonary fibrosis by inhibiting nucleolin and regulating DNA damage repair pathway.
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Prisijungti Registracija
Polyguanylic acid potassium salt (PolyG) has an anti-fibrotic G-quadruplex (G4) structure. It could inhibit the expression of nucleolin, a protein involved in cell proliferation and apoptosis. However, its role in regulating nucleolin in silicosis is still unknown. After instillation of 50 μl of
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