vitamin a palmitate/atrofija

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Studies on the testicular effects of vitamin A palmitate in the Sprague-Dawley rat.

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The purpose of the research was to investigate the mechanism of reported vitamin A-induced testicular degeneration. Three studies of vitamin A toxicity were conducted in male Sprague-Dawley rats; a 10-day study with daily ip injections of retinol palmitate at doses of 0, 115,000 and 230,000

Retinitis pigmentosa inversa.

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BACKGROUND Retinitis pigmentosa (RP) is one of the most common inherited retinal diseases, with a prevalence of about 1 in 3500 to 4500. Retinitis pigmentosa inversa is a rare variant of this disorder characterized by areas of choroidal degeneration with pigment migration and bony spicule formation

Influence of the photostabilizer in the photoprotective effects of a formulation containing UV-filters and vitamin A.

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Vitamin A palmitate has been used in cosmetics; however, studies report that this substance shows photoreactivity that can lead to loss of safety and efficacy. On the other hand, photostabilizers have been used to increase sunscreen photostability and consequently their safety and effectiveness.

Effect of vitamin A supplementation on rhodopsin mutants threonine-17 --> methionine and proline-347 --> serine in transgenic mice and in cell cultures.

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A therapeutic effect of vitamin A supplementation on the course of photoreceptor degeneration, previously reported for patients with retinitis pigmentosa, was tested in two transgenic mouse models of this disease, each carrying a dominant rhodopsin mutation. The threonine-17 --> methionine (T17M)

Retinitis pigmentosa.

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Hereditary degenerations of the human retina are genetically heterogeneous, with well over 100 genes implicated so far. This Seminar focuses on the subset of diseases called retinitis pigmentosa, in which patients typically lose night vision in adolescence, side vision in young adulthood, and

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