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voacristine/voacanga
Nuoroda įrašoma į mainų sritį
6 rezultatus
[Voacanga alkaloids. III. Voacristine: identity with voacangarine and decomposition to iboxygaine and ibogaine].
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[Voacanga alkaloids. IV. Structure of voacryptin and voacristine].
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[Study on the alkaloids constituents from Voacanga africana].
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OBJECTIVE
To study the alkaloids of Voacanga africana.
METHODS
The alkaloids were isolated by normal phase silica gel and Sephadex LH-20 column chromatography. Their structures were elucidated by analysis of spectroscopic data.
RESULTS
Eight alkaloids were isolated and their structures were
Inhibitory effect of Iboga-type indole alkaloids on capsaicin-induced contraction in isolated mouse rectum.
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Voacanga africana (Apocynaceae) is used as an anti-diarrheal medicine in West Africa. In the present study, we investigated the effect of an extract of V. africana and its constituents on smooth muscle contraction induced by capsaicin in mouse rectum, where transient receptor potential vanilloid
Cytotoxic monoterpenoid indole alkaloids isolated from the barks of Voacanga africana Staph.
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A new monoterpenoid indole alkaloid compound (1) and six known monoterpenoid indole alkaloids compounds (2-7) were isolated from the barks of Voacanga africana Staph. The structures were established by spectral analysis as ibogamine-16-carboxylic acid,17,20-didehydro-5,6-dioxo-10-methoxy-methyl
Antibacterial Indole Alkaloids with Complex Heterocycles from Voacanga africana.
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Voacafricines A and B, two unique monoterpenoid indole alkaloids each bearing five fused heterocycles, were obtained from the fruits of Voacanga africana. Their structures were elucidated by extensive spectroscopic methods and computational studies. A plausible biogenetic pathway was proposed from a
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