MDCF-2 prototype with four complimentary food ingredients without powdered milk (rationale: lead with evidence from the recently completed pre-POC clinical trial of promoting growth promoting microbiota and positive effects on growth).

Rice-lentil based RUSF (rationale: reference standard of care for post-SAM, MAM; based on knowledge of its effects on child growth and the gut microbiota)

Microbiota

Complementary Food

Nutrition

MDCF prototype with four complimentary food ingredients without powdered milk (rationale: lead with evidence from the recently completed pre-POC clinical trial of promoting growth promoting microbiota and positive effects on growth

Microbiota Directed Complementary Food-2

Ready to Use Supplementary Food

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Community-based Clinical Trial With Microbiota Directed Complementary Foods (MDCFs) Made of Locally Available Food Ingredients for the Management of Children With Post-severe Acute Malnutrition Moderate Acute Malnutrition (Post-SAM MAM)

Microbiota Directed Complementary Food (MDCF) Post-SAM MAM Trial

Rate of weight gain of the enrolled participants

Information about all proteins that are made in blood, other body fluids, or tissues, at certain times.It will be assayed by Somalogic scan

Refers to having a disease or a symptom of disease. It will be assessed by taking morbidity data

bacterial species whose proportional representation define a healthy gut microbiota as it assembles during the first two postnatal years of life. 'microbiota-for-age Z-score' compares development of a child's fecal microbiota relative to healthy children of similar chronologic age.

International Centre for Diarrhoeal Disease Research, Bangladesh

Washington University School of Medicine

Participants will consume 1 gram of ACCS100 at each meal (up to three times per day) for seven days. The ACCS100 will be administered by mixing a powder sachet into water.

Participants will consume 1 gram of calcium carbonate at each meal (up to three times per day) for seven days. The calcium carbonate will be administered by mixing a powder sachet into water.

Aflatoxicosis

ACCS100 is made from Hydrated Sodium Calcium Aluminosilicate, which is a substance generally recognized as safe by the U.S. FDA.

ACCS100

Calcium carbonate placebo

Makindu Health Center

Evaluation of ACCS100 to Reduce Aflatoxin Exposure in Kenya

Evaluation of the Effectiveness, Acceptability, and Palatability of Air Classified Calcium Silicate (ACCS100) Clay to Reduce Aflatoxin Exposure in a High-risk Community in Kenya

Urine samples will be collected at baseline (Day 0) and daily for seven days during Arm 1 (Days 1-7). Urine samples will also be collected at baseline (Day 13) and daily for seven days during Arm 2 (Days 13-19).

aflatoxin b 1/vemšana

Community-based Clinical Trial With Microbiota Directed Complementary Foods (MDCFs) Made of Locally Available Food Ingredients for the Management of Children With Post-severe Acute Malnutrition Moderate Acute Malnutrition (Post-SAM MAM)

Evaluation of ACCS100 to Reduce Aflatoxin Exposure in Kenya

Vispilnīgākā ārstniecības augu datu bāze, kuru atbalsta zinātne