4 rezultātiem
Seven coumarin derivatives (imperatorin, heraclenin, xanthotoxin, marmesin, chelepin, oxypeucedanin, esculin) and a furan derivative (nimbolide) were screened on 6 Ames tester strains (TA92, TA94, TA97, TA98, TA100, TA102). The eight compounds are chemicals isolated from three Nigerian medicinal
Xanthotoxin, xanthotoxol and marmesin, three coumarins isolated from Afraegle paniculata, have been treated for anti-inflammatory activity following oral administration. The investigations have shown that xanthotoxol and marmesin are devoid of such activity and that xanthotoxin has some activity.
Eight compounds were isolated from the stem bark of the plant Afraegle paniculata. One of them, a dimethyl ether of S-trans-marmin (1), is reported as a new natural product. The structures were determined by comprehensive analyses of their 1D and 2D NMR spectroscopic and HREIMS data. The remaining
The isolation of the coumarins xanthyletin, imperatorin, (+)-heraclenin and xanthoxyletin from the rootbark of A. Paniculata (Schum. et Thonn.) Engl. is reported. From the heartwood of the same plant the coumarins scoparon, xanthotoxin, imperatorin, (+)-heraclenin, 6-hydroxy-7-methoxy-coumarin and