arecoline/kariess

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[Relation of hemodynamic changes in dye shock to the effect of arecoline and to exclusion of the vagus nerves in the region of the abdominal cavity].

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Ielogoties Reģistrēties

Endogenous nitrosation in the oral cavity of chewers while chewing betel quid with or without tobacco.

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Ielogoties Reģistrēties

In order to evaluate endogenous nitrosation in the oral cavity of chewers of betel quid with tobacco (BQT) or without tobacco (BQ), saliva samples were collected from healthy male volunteers after chewing sequentially (i) unmodified BQT or BQ, (ii) BQT or BQ to which proline has been added, and

A study of betel quid carcinogenesis. 1. On the in vitro N-nitrosation of arecoline.

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Ielogoties Reģistrēties

Betel quid chewing is strongly associated with cancer of the oral cavity. Extracts of betel quid are tumorigenic in the experimental animal, but thus far, not a single carcinogen has been detected in the tobacco free quid. This study is based on the hypothesis that during chewing, arecoline, the

Arecoline induced disruption of expression and localization of the tight junctional protein ZO-1 is dependent on the HER 2 expression in human endometrial Ishikawa cells.

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Ielogoties Reģistrēties

BACKGROUND Approximately 600 million people chew Betel nut, making this practice the fourth most popular oral habit in the world. Arecoline, the major alkaloid present in betel nut is one of the causative agents for precancerous lesions and several cancers of mouth among those who chew betel nut.

Study of salivary arecoline in areca nut chewers.

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Ielogoties Reģistrēties

Arecoline, a predominant alkaloid present in arecanut, has been implicated in the pathogenesis of several oral diseases because of its mutagenic and carcinogenic potential. The response of cultured cells to arecoline is highly dependent on its concentration; arecoline stimulates

Arecoline Alters Taste Bud Cell Morphology, Reduces Body Weight, and Induces Behavioral Preference Changes in Gustatory Discrimination in C57BL/6 Mice.

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Ielogoties Reģistrēties

Arecoline, a major alkaloid in areca nuts, is involved in the pathogenesis of oral diseases. Mammalian taste buds are the structural unit for detecting taste stimuli in the oral cavity. The effects of arecoline on taste bud morphology are poorly understood. Arecoline was injected intraperitoneally

Epithelial atrophy in oral submucous fibrosis is mediated by copper (II) and arecoline of areca nut.

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Ielogoties Reģistrēties

Exposure of oral cavity to areca nut is associated with several pathological conditions including oral submucous fibrosis (OSF). Histopathologically OSF is characterized by epithelial atrophy, chronic inflammation, juxtaepithelial hyalinization, leading to fibrosis of submucosal tissue and affects

Fenofibrate exhibits a high potential to suppress the formation of squamous cell carcinoma in an oral-specific 4-nitroquinoline 1-oxide/arecoline mouse model.

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Ielogoties Reģistrēties

The excessive use of areca nut and/or tobacco may induce the production of free radicals and reactive oxygen species, which affect the lipid contents of the cell membrane and are possibly involved in tumorigenic processes in the oral cavity. The aim of this study was to investigate the therapeutic

Mutual interactions among ingredients of betel quid in inducing genotoxicity on Chinese hamster ovary cells.

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Ielogoties Reģistrēties

The purpose of this study is to explore the mutual interactions among the chemical ingredients of betel quid including arecoline, sodium fluoride, catechin and glycyrrhizin in producing genotoxicity on Chinese hamster ovary (CHO) cells using the micronucleus method. Our results show that arecoline

Therapeutic interventions in oral submucous fibrosis: an experimental and clinical study.

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Ielogoties Reģistrēties

BACKGROUND Oral submucous fibrosis (OSF) is a chronic debilitating disease and premalignant condition of the oral cavity and is a serious public health issue in India and many parts of the world. The treatment is still elusive and empirical because of poorly understood etiopathogenesis, which is

Cystatin C: Its role in pathogenesis of OSMF.

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Ielogoties Reģistrēties

Oral Submucous Fibrosis (OSF) is a chronic disorder characterized by fibrosis of the mucosa lining the upper digestive tract involving the oral cavity, oro- and hypopharynx and the upper third of the oesophagus. The alkaloids from areca nut are the most important chemical constituents biologically,

Effects of areca nut extracts on the functions of human neutrophils in vitro.

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Ielogoties Reģistrēties

Aqueous extracts of ripe areca nut without husk (ripe ANE) and fresh and tender areca nut with husk (tender ANE) were examined for their effects on the defensive functions of human neutrophils. Exposure of peripheral blood neutrophils to ripe ANE and tender ANE inhibited their bactericidal activity

Butylidenephthalide abrogates the myofibroblasts activation and mesenchymal transdifferentiation in oral submucous fibrosis.

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Ielogoties Reģistrēties

Oral submucous fibrosis (OSF) is a premalignant disorder in the oral cavity, and areca nut chewing habit has been implicated in the persistent activation of myofibroblasts and the subsequent fibrosis. Therefore, it is critical to ameliorate the excessive activities of myofibroblasts prior to the

Inhibitory effect of GMI, an immunomodulatory protein from Ganoderma microsporum, on myofibroblast activity and proinflammatory cytokines in human fibrotic buccal mucosal fibroblasts.

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Ielogoties Reģistrēties

Oral submucous fibrosis (OSF) has been indicated as one of the oral potentially malignant disorders. Epidemiological studies have attributed this pathological fibrosis to the habit of areca nuts chewing, which causes chronic inflammation and persistent activation of myofibroblasts in the oral

[Collagen content and types in oral submucous fibrosis].

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Ielogoties Reģistrēties

Oral submucous fibrosis is a chronic disease of the oral cavity. The basic histological change which occurs is a fibroelastic transformation of the connective tissue in the laminal propria layer associated with epithelial atrophy. The etiology of the disease is uncertain, but there is a close

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