erycibe/alkaloid

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[The synthesis and bioactivities of cholinergic tropane alkaloids].

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Ielogoties Reģistrēties

Ten analogs of baogongteng A, the natural cholinergic tropane alkaloid isolated from Erycibe obtusifolia Benth, were designed and synthesized. The tropane skeleton was kept unchanged, while the substituting groups on N and C3 were modified. In myotic experiments in rabbits 3-paramethyl

[The synthesis and pharmacological activities of analogs of erycibe alkaloid II].

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Ielogoties Reģistrēties

The C2 deoxy and C6 electron isosteric analogs of a new antiglaucoma agent, erycibe alkaloid II, were designed and synthesized. The main pharmacological results were as follows: 1. The C2-OH in erycibe alkaloid II was one of the key groups for its myotic activity; 2. It was worth noting that

[A preliminary report on treatment of glaucoma with an alkaloid from erycibe obtusifolia Benth (author's transl)].

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Ielogoties Reģistrēties

[Chemical constituents of the stems of Erycibe schmidtii Craib].

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Ielogoties Reģistrēties

Seven compounds were isolated from the stems of Erycibe schmidtii for the first time. They were identified as hexadecanoic acid, beta-sitosterol, scopoletin, chlorogenic acid, daucosterel, scopolin and an alkaloid-baogongteng C.

Acute Erycibe henryi Prain ("Ting Kung Teng") poisoning.

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Ielogoties Reģistrēties

Erycibe henryi Prain ("Ting Kung Teng"), a species of Convolvulaceae, has been used in Chinese medicine to relieve pain involving the musculoskeletal system, such as arthritis, sciatica, and traumatic tissue swelling. E. henryi can be mistaken for another herbal plant, Tripterygium wilfordii Hook F,

[Studies on synthesis of baogongteng A--a new myotic agent].

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Ielogoties Reģistrēties

Baogongteng A, isolated from Erycibe obtusifolia Benth., is a new tropane alkaloid used for treating glaucoma. Using synthetic 6 beta-acetoxy-tropinone as starting material, racemic Baogongteng A(8) was synthesized. Synthetic Baogongteng A also shows myotic activities in rabbits, but the potency is

Organometallic enantiomeric scaffolding: organometallic chirons. Total synthesis of (-)-Bao Gong Teng A by a molybdenum-mediated [5 + 2] cycloaddition.

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Ielogoties Reģistrēties

Bao Gong Teng A, an optically active tropane alkaloid with hypotensive and miotic activity isolated from the Chinese herb Erycibe obtusifolia Benth, was synthesized by an "organometallic chiron" strategy in which single enantiomers of TpMo(CO)(2)(eta(3)-pyridinyl) complexes are produced in quantity

Qualitative and quantitative analysis of Porana sinensis Hemsl by UHPLC-Q-Exactive MS, TLC autographic method and DART-MS.

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Ielogoties Reģistrēties

Erycibe obtusifolia and E. schmidtii are widely used in traditional Chinese medicine (TCM) to treat joint pain and rheumatoid arthritis. With the reduction of wild E. obtusifolia and E. schmidtii resources, Porana sinensis has been widely used as a substitute. However, few studies have

Medicinal herb Erycibe henri Prain ("Ting Kung Teng") resulting in acute cholinergic syndrome.

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Ielogoties Reģistrēties

A 73-year-old man consumed a decoction of the medicinal herb Erycibe henri Prain ("Ting Kung Teng"), as recommended in traditional Chinese medicine for arthritis. Shortly, he developed a cholinergic syndrome that included dizziness, diaphoresis, chills, lacrimation, salivation, rhinorrhea, nausea,

Toxicology and the chemical foundation of plants of Erycibe.

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Ielogoties Reģistrēties

Erycibe is a relatively small genus in the family Convolvulaceae with over 10 identified species. Some Erycibe plant species are purportedly toxic at high doses. However, few toxicology studies have been conducted on those species. In this study, the toxicity of 40% ethanolic extracts of

A concise stereoselective synthesis of (-)-erycibelline.

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Ielogoties Reģistrēties

(-)-Erycibelline, the dihydroxynortropane alkaloid isolated from Erycibe elliptilimba Merr. et Chun., was synthesized using a cyclic nitrone as advanced intermediate, wherein the key step was the SmI(2)-induced intramolecular reductive coupling of cyclic nitrone with aldehyde which resulted in good

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