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flavone/hypoxia

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[Effects of flavones extracted from Portulaca oleracea on ability of hypoxia tolerance in mice and its mechanism].

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OBJECTIVE To identify anti-hypoxia ingredients extracted from Portulaca oleracea and to find out the possible mechanism of its anti-hypoxia actions. METHODS Seventy mice were randomly divided into seven groups which were untreated (normal saline), ginsenosides-treated, polysaccharide-treated, acidic
Many flavonoids have cardioprotection against myocardial ischemia/reperfusion (I/R) injury. Total flavones from Rhododendron simsii Planch flower (TFR) can protect myocardial ischemic injuries. However, its protective mechanism is still unknown. The present study was designed to investigate the
This study aimed to determine the effects of Bauhinia championii flavone (BCF) on hypoxia-reoxygenation (H/R) induced apoptosis in H9c2 cardiomyocytes and to explore potential mechanisms. The H/R model in H9c2 cardiomyocytes was established by 6 h of hypoxia and 12 h of reoxygenation. Cell viability
OBJECTIVE To investigate the effects of flavone extracted from the leaves of Diospyros kaki on the apoptosis of rat cardiac myocytes induced by hypoxia-reoxygenation and advanced glycation end products in vitro. METHODS The cardiac myocytes were isolated from neonatal SD rats and cultured in vitro
To study the effects of total flavones of Rhododendra simsii Planch flower (TFR) on hypoxia/reoxygenation (H/R) injury in rat hippocampal neurons and its underlying mechanism.

METHOD
Model of H/R was established in newborn rat primary cultured
In the present study, we for the first time explored the protective effect of LOB (Chrysoeriol 7-O-[β-D-glucuronopyranosyl-(1→2)-O-β-D-glucuronopyranoside]) on myocardial ischemia-reperfusion (I/R) injury in a rat model and on hypoxia-reoxygenation (H/R) injury in a rat myocardium cell line. An I/R

Induction of hypoxia in the KHT sarcoma by tumour necrosis factor and flavone acetic acid.

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The interaction of FAA or TNF with radiation was studied in the murine KHT sarcoma. When used alone both agents showed a dose- and time-dependent toxicity towards the tumour cells and significantly reduced tumour blood flow within 1 h of treatment. When used in combination with radiation, both TNF
The present study investigates the potential signal pathway of acacetin in cardioprotection against ischemia/reperfusion injury using an in vitro hypoxia/reoxygenation model in primary cultured neonatal rat cardiomyocytes and H9C2 cardiomyoblasts. It was found that acacetin (0.3-3 μM) significantly

[Effect of flavone from Crataegus on gas exchange in anoxia].

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[Clinical circulatory studies of the effect of flavone from Crataegus on oxygen-deficiency breathing].

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Flavones and flavonols may have clinical potential as CK2 inhibitors in cancer therapy.

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The serine-threonine kinase CK2, which targets over 300 cellular proteins, is overexpressed in all cancers, presumably reflecting its ability to promote proliferation, spread, and survival through a wide range of complementary mechanisms. Via an activating phosphorylation of Cdc373, a co-chaperone

Effects of flavone on the oxidation-induced injury of retinal pigment epithelium cells.

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Ielogoties Reģistrēties
OBJECTIVE To investigate the effect of flavone on oxidation-induced injury in retinal pigment epithelium cells. METHODS In in vivo studies, NaIO(3)-induced RPE degeneration in rat eyes was treated with 0.5% flavone eye drops 3 times a day for 1 week before and 4 weeks after NaIO(3) injection. At the
BACKGROUND EGb761 is a standard extract from the leaves of Ginkgo biloba (Yinxing) containing ginkgo-flavone glycosides and terpenoid. The flavonoid components of EGb761 scavenge free radicals and protect myocardia from ischemia-reperfusion injury. The present study aims to determine the effects of
OBJECTIVE Baicalin, a natural flavone, has antithrombotic, antihyperlipidemic and antiinflammortory activity. It can also inhibit cancer cell proliferation and reduce brain cell apoptosis. This study aimed to elucidate the effect of baicalin on the excessive proliferation of human pulmonary arterial

Effects of Scrambling trumpet Creeper flavone on transient cerebral ischemia model (TIA) in rats.

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Ielogoties Reģistrēties
To investigate the effects of Scrambling Trumpet Creeper flavone on neurological function score, brain tissue lesion and related biochemical indexes in rat TIA model. Methods: TIA model was induced by tail vein injection of t-butanol (t-BHP). The rats in each administration group were given large,
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