glycosidase/asiņošana

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Purification and characterization of two high molecular weight hemorrhagic toxins from Crotalus viridis viridis venom using monoclonal antibodies.

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Ielogoties Reģistrēties

Two high mol. wt hemorrhagic toxins were purified from Crotalus viridis viridis venom using HPLC anion exchange and monoclonal antibody affinity chromatography following initial separation by HPLC with a preparative DEAE column. The fraction from the initial column having the highest hemorrhagic

Partial characterization of the human erythrocyte receptor for rabbit haemorrhagic disease virus.

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Ielogoties Reģistrēties

An important, well known property of the rabbit haemorrhagic disease virus is its ability to agglutinate human red blood cells. Accordingly, red cells from human adult donors were agglutinated despite their blood group ABO status, and treatments with proteases or glycosidases did not prevent

Characterization of intramolecular disulfide bonds and secondary modifications of the glycoprotein from viral hemorrhagic septicemia virus, a fish rhabdovirus.

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Ielogoties Reģistrēties

Viral hemorrhagic septicemia virus (VHSV) infections cause high losses in cultured rainbow trout in Europe. Attempts to produce a recombinant vaccine based on the transmembrane glycoprotein (G protein) have indicated that proper folding is important for the antigenicity and immunogenicity of the

The effect of treatment on the activity of salivary proteases and glycosidases in adults with advanced periodontitis.

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Ielogoties Reģistrēties

Enzyme activity in whole saliva of trypsin-like protease, elastase-like protease, general protease, and three glycosidases was measured by colorimetric assays, using synthetic substrates. A study group of 24 adults with advanced periodontitis was compared to a control group of 25 subjects with

Variation of fibrinogen oligosaccharide structure in the acute phase response: Possible haemorrhagic implications.

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Ielogoties Reģistrēties

BACKGROUND Fibrinogen is an acute phase glycoprotein whose concentration increases in response to trauma. The newly synthesised protein is functionally enhanced and it is known that treatment with neuraminidase increases the rate of fibrin polymerisation. To explore this, we examined the differences

Measurement of alpha-glucosidase activity in serum from patients with cystic fibrosis or pancreatitis.

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Ielogoties Reģistrēties

We measured the activity of a non-lysosomal alpha-glucosidase with pH optimum near 6.0 in serum from a wide variety of patients, using the fluorogenic substrate, 4-methylumbelliferyl-alpha-D-glucopyranoside. Acutely ill patients with cystic fibrosis (CF) demonstrated significant increases in

Oligosaccharide residues of Loxosceles intermedia (brown spider) venom proteins: dependence on glycosylation for dermonecrotic activity.

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Ielogoties Reģistrēties

Loxosceles spp. (brown spider) envenomation has been reported to provoke dermonecrosis and haemorrhage at the bite site (a hallmark of accidents) and, to a lesser extent, thrombocytopenia, hemolysis and disseminated intravascular coagulation in some cases. Using lectin-immunolabeling,

Verotoxin and ricin have novel effects on preproendothelin-1 expression but fail to modify nitric oxide synthase (ecNOS) expression and NO production in vascular endothelium.

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Ielogoties Reģistrēties

Interaction of bipartite Escherichia coli O157-derived verotoxins (VTs) 1 and 2 (Shiga toxin 1 and 2) with vascular endothelium is believed to play a central role in the pathogenesis of the thrombotic microangiopathy and ischemic lesions characteristic of hemolytic uremic syndrome and of E. coli

A man with type III glycogenosis associated with cirrhosis and portal hypertension.

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Ielogoties Reģistrēties

Type III glycogenosis, an inherited disorder of glycogen metabolism that results from reduced or absent activity of the enzyme amylo-1,6-glycosidase (debranching enzyme), has not been frequently associated with cirrhosis and portal hypertension in adults. An adult Caucasian man with well-document

Enterohaemorrhagic Escherichia coli.

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Ielogoties Reģistrēties

Enterohaemorrhagic Escherichia coli produces Verotoxins (Shiga-like toxins) and causes diarrhoea, haemorrhagic colitis and haemorrhagic uraemic syndrome. The mode of action of the Shiga toxin family has been well characterized in numerous studies which have demonstrated that the toxin has RNA

Escherichia coli cytotoxins and enterotoxins.

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Ielogoties Reģistrēties

Vero cell cytotoxins and cytotonic enterotoxins produced by E. coli are toxic proteins, which have been implicated in a number of specific diseases in humans and animals. Nomenclature for these toxins is complicated by the existence of different names for the same toxin. The Vero cell cytotoxins are

Escherichia coli Shiga toxin.

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Ielogoties Reģistrēties

The Stx family contains two types called Stx1 (verotoxin 1: VT1 or Shiga-like toxin: SLT1) and Stx2 (VT2, SLT2); both toxins are encoded by bacteriophages. Stx1 is identical to Shiga toxin produced by Shigella dysenteriae type I. Stx2 is heterogeneous and immunologically different from Stx1.

Isolation and characterisation of a kallikrein-like enzyme from Agkistrodon halys pallas snake venom.

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Ielogoties Reģistrēties

BACKGROUND Viper snake venoms contain a great variety of toxic proteins. These components mediate their toxicity by either stimulating or inhibiting the haemostatic system of human victims or experimental animals, resulting in common clinical complications of blood clotting or uncontrolled

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