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molybdenum/hypoxia

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The unique ability of the tuberculosis (TB) bacillus, Mycobacterium tuberculosis, to persist for long periods of time in lung hypoxic lesions chiefly contributes to the global burden of latent TB. We and others previously reported that the M. tuberculosis ancestor underwent massive episodes of

Molybdenum isotope evidence for widespread anoxia in mid-Proterozoic oceans.

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How much dissolved oxygen was present in the mid-Proterozoic oceans between 1.8 and 1.0 billion years ago is debated vigorously. One model argues for oxygenation of the oceans soon after the initial rise of atmospheric oxygen approximately 2.3 billion years ago. Recent evidence for H(2)S in some

[Effects of molybdenum and hypoxia on the cardiovascular system of experimental animals].

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The investigation had the purpose to study an impact of environmental pollution by molybdenum-containing wastes, and Mo dose-dependent effect on the cardiac structure and function in hypoxic conditions. The experiments were performed with white Wistar rats using electrophysiological and histological

Comment on "Molybdenum isotope evidence for widespread anoxia in mid-Proterozoic oceans".

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Investigation of molybdenum cofactor deficiency due to MOCS2 deficiency in a newborn baby.

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BACKGROUND Molybdenum cofactor deficiency (MOCD) is a severe autosomal recessive neonatal metabolic disease that causes seizures and death or severe brain damage. Symptoms, signs and cerebral images can resemble those attributed to intrapartum hypoxia. In humans, molybdenum cofactor (MOCO) has been

Molybdenum scavenging by iron monosulfide.

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Molybdenum profiles in dated sediment cores provide useful historical information about anoxia in anthropogenically impacted natural waters but would be of greater service if Mo fixation mechanisms were better understood. Here, we explore Mo scavenging by precipitated FeS in a model system

Tissue processing of nitrite in hypoxia: an intricate interplay of nitric oxide-generating and -scavenging systems.

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Although nitrite (NO(2)(-)) and nitrate (NO(3)(-)) have been considered traditionally inert byproducts of nitric oxide (NO) metabolism, recent studies indicate that NO(2)(-) represents an important source of NO for processes ranging from angiogenesis through hypoxic vasodilation to ischemic organ

Molybdenum-containing nitrite reductases: Spectroscopic characterization and redox mechanism.

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OBJECTIVE This review summarizes the spectroscopic results, which will provide useful suggestions for future research. In addition, the fields that urgently need more information are also advised. BACKGROUND Nitrite-NO-cGMP has been considered as an important signaling pathway of NO in human cells.

Cobalt-alloy implant debris induce HIF-1α hypoxia associated responses: a mechanism for metal-specific orthopedic implant failure.

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The historical success of orthopedic implants has been recently tempered by unexpected pathologies and early failures of some types of Cobalt-Chromium-Molybdenum alloy containing artificial hip implants. Hypoxia-associated responses to Cobalt-alloy metal debris were suspected as mediating this

Oxygen-Vacancy-Tunable Electrochemical Properties of Electrodeposited Molybdenum Oxide Films.

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Ielogoties Reģistrēties
Molybdenum oxides have been widely studied in recent years, owing to their electrochromic properties, electrocatalytic activities for hydrogen evolution reactions (HERs) and excellent energy storage performance. These characteristics strongly depend on the valence states of Mo in the oxides such as
Tumor hypoxia significantly diminishes the efficacy of reactive oxygen species (ROS)-based therapy, mainly because the generation of ROS is highly oxygen dependent. Recently reported hypoxia-irrelevant radical initiators (AIBIs) exhibit promising potential for cancer therapy under different oxygen

Nitrogen isotope fractionation by alternative nitrogenases and past ocean anoxia.

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Biological nitrogen fixation constitutes the main input of fixed nitrogen to Earth's ecosystems, and its isotope effect is a key parameter in isotope-based interpretations of the N cycle. The nitrogen isotopic composition (δ(15)N) of newly fixed N is currently believed to be ∼-1‰, based on

Amorphous Mo5O14-Type/Carbon Nanocomposite with Enhanced Electrochemical Capability for Lithium-Ion Batteries.

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An amorphous MomO3m-1/carbon nanocomposite (m ≈ 5) is fabricated from a citrate-gel precursor heated at moderate temperature (500 °C) in inert (argon) atmosphere. The as-prepared Mo5O14-type/C material is compared to α-MoO3 synthesized from the

Posttranslational inactivation of human xanthine oxidoreductase by oxygen under standard cell culture conditions.

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Xanthine oxidoreductase (XOR) catalyzes the final reactions of purine catabolism and may account for cell damage by producing reactive oxygen metabolites in cells reoxygenated after hypoxia. We found a three- to eightfold higher XOR activity in cultured human bronchial epithelial cells exposed to

Lung injury and oxidoreductases.

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Acute lung injury represents a wide spectrum of pathologic processes, the most severe end of the spectrum being the acute respiratory distress syndrome. Reactive oxygen intermediates have been implicated as important in the pathobiochemistry of acute lung injury. The endogenous sources that
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