4 rezultātiem
Allyl isothiocyanate, a naturally occurring compound, component of oil of mustard and human food plants such as cabbage, cauliflower and horseradish, has up to now been regarded as nonmutagenic in bacterial mutagenicity testing systems. Recently, however, it was found to cause transitional-cell
Studies were conducted to evaluate the ability of dietary dried cabbage supplements to inhibit pancreatic carcinogenesis in hamsters and skin tumorigenesis in mice. Pancreatic cancer was induced by treatment with 40 mg/kg body wt N-nitrosobis-(2-oxopropyl)amine (BOP). Cabbage was fed from before
BACKGROUND
The objective of the present study was to determine if modulation of GSH-dependent antioxidant protective system by Brassica oleraceae var capitata might inhibit the molecular mechanism of skin tumor promotion.
METHODS
In a two stages skin carcinogenesis model, the protocol used included
We report the chemopreventive property of an ethanolic extract of the seeds of Brassica compestris var sarason (mustard seed) on DMBA (7,12 dimethylbenz(a)anthracene induced skin papillomagenesis in male Swiss albino mice. A significant reduction in the values of tumour incidence, tumour burden and