4 rezultātiem
BACKGROUND
Solanum sisymbriifolium Lam. (Solanaceae), commonly known as sticky nightshade, is traditionally used for central nervous system (CNS) disorders. Although solasodine has been isolated from this plant, little is known about its anticonvulsant and CNS depressant actions.
OBJECTIVE
We
Although we are familiar with common British plants that are poisonous, such as Atropa belladonna (deadly nightshade) and Aconitum napellus (monkshood), the two most poisonous plants in the British Flora are Oenanthe crocata (dead man's fingers) and Cicuta virosa (cowbane). In recent years their
BACKGROUND
Solanum nigrum is claimed in traditional medical practice, to be useful in the treatment of epilepsy in some parts of Nigeria.
OBJECTIVE
To study the anti-convulsant property of the aqueous extract of the leaves of S. nigrum in chicks, mice and rats.
METHODS
Aqueous extracts were
The crude ethanolic extract prepared from the stem bark of Solanum pseudo-quina produced excitatory effects dominated by convulsions in rats and mice. Solvent extraction followed by alumina column chromatography resulted in the isolation of a pharmacologically active material (AP) which was