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Management of small cell lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition).

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Ielogoties Reģistrēties

OBJECTIVE This guideline is for the management of patients with small cell lung cancer (SCLC) and is based on currently available information. As part of the guideline, an evidence-based review of the literature was commissioned that enables the reader to assess the evidence as we have attempted to

A critical review of the role of definitive radiation therapy in bladder cancer.

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Ielogoties Reģistrēties

The role of radiation therapy in the management of bladder cancer continues to be controversial. Attention to the issue of response to treatment, instead of overall survival, ultimate local control and quality of life, has hampered progress in determining the optimal-treatment strategy for patients

[The story about Hodgkin's lymphoma].

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Ielogoties Reģistrēties

The exciting story about Hodgkin's lymphoma is 170 years old. Today, we know a lot about biology of this B cell neoplasma (derived from the germinative center), and the diagnostic standard criteria are clearly defined and accepted. Although the definition of prognostic factors for early disease

The role of pharmacokinetic and pharmacodynamic studies in the planning of protocols for the treatment of childhood cancer.

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Ielogoties Reģistrēties

The chemosensitive nature of many childhood cancers means that chemotherapy has a greater role in therapy than in adult practice. However, the present methods, schedules of administration and combinations have often been derived form historical precedent rather than from pharmacological knowledge.

Chemical Characterization, Antileishmanial Activity, and Cytotoxicity Effects of the Essential Oil from Leaves of Pluchea carolinensis (Jacq.) G. Don. (Asteraceae).

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Ielogoties Reģistrēties

Current strategies to control leishmaniasis are mainly based on chemotherapy. However, none of the available drugs can be considered to be ideal to treat this disease. Because of the hydrophobic nature and bioactivities of their components, essential oils (EOs) can be considered as important sources

Notch and Wnt signaling pathway in cancer: Crucial role and potential therapeutic targets (Review).

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Ielogoties Reģistrēties

There is no radical cure for all cancer types. The most frequently used therapies are surgical treatment, radiotherapy and chemotherapy. However, recrudescence, radiation resistance and chemotherapy resistance are the most challenging issues in clinical practice. To address these issues, they should

Acute promyelocytic leukemia (APL): remaining challenges towards a cure for all.

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Ielogoties Reģistrēties

The application of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) has revolutionized the treatment of acute promyelocytic leukemia (APL). More than 80-90% of patients are expected to be cured with a combination of ATRA, ATO and/or chemotherapy. In this review, we focus on the remaining

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