An antiobestic agent of the present invention having antiobestic effect, carbohydrase inhibitory effect, blood sugar increase inhibitory effect, monosaccharide absorption inhibitory effect, cholic acid adsorptive excretion promoting effect, cholesterol lowering effect, blood triglyceride lowering effect and lipase inhibitory effect and being useful not only as an antiobestic agent but also as an antilipotrophic agent, an antihyperlipemic agent, an antiarteriosclerotic agent and an antidiabetic agent. Tamarind seed coat extract containing a large amount of procyanidin, which is a trimer represented by the following formula and serves as the active ingredient in the present invention, exhibits a potent antiobestic effect as such without the need for further purification. The antiobestic agent of the present invention is usable as a carbohydrase inhibitor, a blood sugar increase inhibitor, a monosaccharide absorption inhibitor, a cholic acid adsorptive excretion promoter, a cholesterol lowering agent, a blood triglyceride lowering agent and a lipase inhibitor. Moreover, use of the antiobestic agent makes it possible to produce foods or beverages and animal feeds having these effects, thus contributing to the relief or prevention of diabetes and obesity in our daily life ##STR1##

Suntory Limited

Antiobestic agent containing procyanidin as the active ingredient

This invention provides carbohydrate absorption inhibitor derived from evening primrose seed which is significantly effective to prevent and cure diabetes mellitus and prevent obesity, and the manufacturing method of the same.Carbohydrate absorption inhibitor in this invention is characterized that the effective component is an alcohol extract of evening primrose seed. The aforementioned evening primrose seed is preferably a defatted evening primrose seed. Extracting solvent of the aforementioned evening primrose seed is preferably ethanol, or preferably a 70 to 85% (v/v) aqueous ethanol. Also, this invention is characterized that the carbohydrate absorption inhibitor is an effective component of polyphenol derived from evening primrose seed. The polyphenol is preferably one or more substances selected from among gallic acid, ellagic acid, catechin, pentagalloylglucose, procyanidin, and proantocyanidin. The manufacturing method of the carbohydrate absorption inhibitor in this invention is characterized to be composed of the following processes A to C. Process A: evening primrose is compressed, oil is separated then the compressed cake is obtained. Process B: The aforementioned compressed cake is defatted in fat-soluble organic solvent, and defatted substance is obtained. Process C: The aforementioned defatted substance is extracted by alcohol, and then this extracted liquid is concentrated or evaporated.

procyanidin a 1/aptaukošanās

Antiobestic agent containing procyanidin as the active ingredient

Carbohydrate absorption inhibitor and method for manufacturing the same

Vispilnīgākā ārstniecības augu datu bāze, kuru atbalsta zinātne