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9 rezultātiem
Dietary supplement enhancing the muscular energy metabolism, comprising an alkanoyl carnitine and ribose
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
BACKGROUND OF THE INVENTION
The present invention relates to a health food/dietary supplement comprising as its characterising ingredients an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine and propionyl L-carnitine or their pharmacologically acceptable salts or
Dietary supplement enhancing the muscular energy metabolism, comprising an alkanoyl carnitine and ribose
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
BACKGROUND OF THE INVENTION
The present invention relates to a health food/dietary supplement comprising as its characterising ingredients an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine and propionyl L-carnitine or their pharmacologically acceptable salts or
Methods and compositions for inhibiting progression to chronic cardiac failure
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
FIELD OF THE INVENTION
This invention relates generally to compositions and methods for reducing progression to heart failure as a consequence of cardiac stress.
BACKGROUND OF THE INVENTION
Without limiting the scope of the invention, its background is described in connection with the existing
Small molecule inhibitors of PARP activity
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
BACKGROUND OF THE INVENTION
Poly ADP-ribose synthetase 1 (or PARP-1) is a dimeric nuclear protein, with two 113 kDa polypeptide subunits, each consisting of three functional domains: the DNA binding amino terminal domain with two zinc fingers for recognition of single and double strand DNA breaks,
Pharmaceutically acceptable salts of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
BACKGROUND OF THE INVENTION
The present invention relates to pharmaceutically acceptable salts of an amide substituted indazole which are inhibitors of the enzyme poly(ADP-ribose)polymerase (PARP), previously known as poly(ADP-ribose)synthase and poly(ADP-ribosyl)transferase. The compounds of the
Isoquinoline compounds and medicinal use thereof
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
This application is a 371 of PCT/JP03/14904 filed Nov. 21, 2003.
TECHNICAL FIELD
The present invention relates to a novel isoquinoline compound and a pharmaceutical agent containing same as an active ingredient.
BACKGROUND ART
Poly(ADP-ribose)polymerase, hereinafter to be abbreviated as "PARP", is
Isoquinoline compound and pharmaceutical use thereof
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a novel isoquinoline compound and a pharmaceutical agent containing same as an active ingredient.
BACKGROUND ART
Poly(ADP-ribose)polymerase, hereinafter sometimes to be abbreviated as "PARP", is an intranuclear enzyme that utilizes
Isoquinoline compound and pharmaceutical use thereof
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a novel isoquinoline compound and a pharmaceutical agent containing same as an active ingredient.
BACKGROUND ART
Poly(ADP-ribose)polymerase, hereinafter sometimes to be abbreviated as "PARP", is an intranuclear enzyme that utilizes
Isoquinoline compound and pharmaceutical use thereof
Rakstu tulkošanu var veikt tikai reģistrēti lietotāji
Ielogoties Reģistrēties
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a novel isoquinoline compound and a pharmaceutical agent containing same as an active ingredient.
BACKGROUND ART
Poly(ADP-ribose)polymerase, hereinafter sometimes to be abbreviated as "PARP", is an intranuclear enzyme that utilizes
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