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Real-time 3-Dimensional Echocardiography for Assessment of Cardiac Function and Congenital Heart Disease

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Ielogoties Reģistrēties

I. SPECIFIC AIMS 1. To measure and calculate Z Scores of cardiac structures and function using 3-DE in a large cohort of healthy infants, children, and adolescents. 2. To investigate the utility of 3-DE in infants, children and adolescents with congenital and acquired heart disease. II. BACKGROUND

Scanner and Transplant Heart Patients Protocol

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Ielogoties Reģistrēties

Background: Heart transplantation is a major advance in the care of patient with terminal heart failure. But, despite the spectacular prognosis improvement obtained with this treatment, coronary vasculopathy remains the leading cause of decreased survival after the first year post-transplantation

Comparison Between Endoscopic Stenting and Cholecystojejunostomy for PreoperativeDrainage Before Pancreaticoduodenectomy

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Ielogoties Reģistrēties

Hypothesis preoperative biliary decompression by Cholecystojejunostomy will reduce infective complication by 23% as compared to endocopic stenting INTRODUCTION Pancreaticoduodenectomy has been associated with a substantial postoperative morbidity and mortality. Advances in surgical techniques and

The Incidence of Nontuberculous Mycobacterial Pulmonary Infection in Bilateral Bronchiectasis and Bronchiolitis

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Ielogoties Reģistrēties

Study Population During the study period helical thin-section thoracic CT scans will obtained in patients in whom a diagnosis of bronchiectasis was known or who were suspected of having bronchiectasis on the basis of clinical symptoms and signs of a chronic cough and sputum production. One chest

The Use of Manuka Honey to Improve Healing After Third Molars Surgery

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Ielogoties Reģistrēties

Sufficient evidence exists recommending the use of honey in the management of acute wounds and burns. Studies revealed that the healing effect of honey could be classified by its antibacterial, antiviral, anti-inflammatory and antioxidant properties of its components. Manuka honey has been shown to

Study of Dovitinib (TKI258) in Adenoid Cystic Carcinoma

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Ielogoties Reģistrēties

Adenoid cystic carcinoma (ACC) is an uncommon malignancy that arises in secretory glands. The most common sites for the disease are the major and minor salivary glands but these tumors may also arise in the nasal cavity, lacrimal gland, tracheobronchial tree, breast or vulva. The mainstay of

Hyperpolarized Magnetic Resonance Imaging in Asthma Pre- and Post-Bronchial Thermoplasty

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Ielogoties Reģistrēties

This is a one year, single centre randomized controlled trial. Subjects will be identified through the London Asthma Centre located at St. Joseph's Hospital and from Hamilton at St. Joseph's Healthcare, and will be given a letter of information for the study. The study will only recruit subjects

CABI: Antibiotic Duration for Complicated Intra-ABdominal Infection

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Ielogoties Reģistrēties

Complicated intra-abdominal infection (CABI) extends beyond the hollow viscus of origin into the peritoneal space and is associated with either abscess formation or peritonitis [Solomkin 2010]. CABIs are heterogeneous in aetiology and include spontaneous infections arising from a perforated viscus,

Study of Variation Over Time in the Oral Microbiome

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Ielogoties Reģistrēties

The Human Microbiome Project (HMP), started in 2008, aimed to characterize the microbial communities on the skin, in the oral and nasal cavities, and in the gastrointestinal and urogenital tracts. This project cross-sectionally described the microbial communities in a healthy human population, but

The Anti-allergic Effects of Specific Probiotics

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Ielogoties Reģistrēties

Probiotics are "live microorganisms which when administered in adequate amounts confer a health benefit on the host". Many studies have been performed which indicate that probiotics can temporarily modify the composition of gut microbiota, and potentially these can reduce susceptibility to allergy

Living Donor Liver Transplantation With Two Stage Hepatectomy for Patients With Isolated, Irresectable Colorectal Liver Metastases

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Ielogoties Reģistrēties

Purpose The purpose of the present study is to evaluate a two-stage hepatectomy with a left-lateral living donor liver transplantation and right portal vein ligation for treatment of otherwise irresectable liver metastases of colorectal carcinoma in curative intent. Study setting The study is an

Surgical Management of Primary Spontaneous Pneumothorax

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Ielogoties Reģistrēties

pneumothorax is defined as air or gas accumulated in the pleural cavity. Spontaneous pneumothorax can be classified as either primary or secondary. Primary spontaneous pneumothorax , which is defined as a pneumothorax without underlying lung disease, predominantly occurs in young, thin males. It is

Changes in Adaptive Immune Responses and Effector Cell Responses Upon Nasal Allergen Exposure - a Pilot Study

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Ielogoties Reģistrēties

Rational of the Study Previous studies on the dynamics of the in vivo clinical and immunological responses to nasal allergen have focused on particular parameters but have not addressed the kinetics of the interplay between the different factors (i.e. allergen-specific IgE levels, local IgE and

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