Biologically active xanthone derivatives, as well as compositions prepared from such derivatives, possessing anti-cancer activity, anti-inflammatory activity, anti-obesity activity, and/or hair growth promotion activity, and a method for producing such derivatives and compositions. The derivatives are obtained by utilizing a heating, extracting and condensing system that efficiently recovers the derivatives from a raw material.

Kuboyama Bio Ken Inc.

Xanthone derivatives, method of production thereof, and pharmaceutical composition containing the same

Pharmaceutical, cosmetic, nutraceutical and dietary compositions derived from Garcinia mangostana are rich in .gamma.-mangostin and other demethylated xanthones. These compositions exhibit potent antioxidative activity and reduce inflammation. These compositions may be used in a method of treating TNF-.alpha., and aP2 mediated disorders. The compositions are prepared by subjecting a hydroalcoholic extract of fruit pericarp (fruit hull) of Garcinia mangostana, wherein said hydroalcoholic extract comprises predominantly .alpha.-mangostin, to demethylation in the presence of a Lewis acid, an organic base and a catalyst.

xanthone/iekaisums

Xanthone derivatives, method of production thereof, and pharmaceutical composition containing the same

Nutraceutical composition from Garcinia mangostana

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