Effects of Almond Versus Pistachio on Weight Loss

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Спонзори

Novindiet Clinic

Соработници

University of Nottingham

Tehran University of Medical Sciences

КЛИНИЧКО ИСПИТУВАЊЕ: NCT03120455

BioSeek: NCT03120455

Клучни зборови

Апстракт

The purpose of the current study is comparing the effect of almond and pistachio, as the two common types of nuts, consumption on healthy obese and overweight female who following a hypocaloric diet for 12 weeks. The secondary aim of the current study is to evaluate of these two type of nuts on other cardiometabolic risk factors.

Датуми

Последен пат проверено:	02/28/2018
Прво доставено:	04/14/2017
Поднесено е проценето запишување:	04/14/2017
Прво објавено:	04/18/2017
Последното ажурирање е доставено:	03/27/2018
Последно ажурирање објавено:	03/28/2018
Крај на датумот на започнување на студијата:	06/04/2017
Проценет датум на примарно завршување:	11/12/2017
Проценет датум на завршување на студијата:	01/14/2018

Состојба или болест

Obesity

Overweight

Интервенција / третман

Behavioral: Almond group (AG)

Behavioral: Pistachio group (PG)

Behavioral: Nut Free (NFG, CG)

Фаза

Групи за раце

Рака	Интервенција / третман
Experimental: Almond group (AG) Obese or overweight female adults will be randomly allocated to have have almond as afternoon snack while they have a hypoenergetic diet.	Behavioral: Almond group (AG) Obese or overweight female adults will be randomly allocated to have almond as afternoon snacks, while they have a hypoenergetic diet.
Active Comparator: Pistachio group (PG) Obese or overweight female adults will be randomly allocated to have have Pistachio as afternoon snack while they have a hypoenergetic diet.	Behavioral: Pistachio group (PG) Obese or overweight female adults will be randomly allocated to have Pistachio as afternoon snacks, while they have a hypoenergetic diet.
Placebo Comparator: Nut Free (NFG, CG) Obese or overweight female adults are asked to avoid all nuts, seeds, and nut products while they have a hypoenergetic diet. , as the control group.	Behavioral: Nut Free (NFG, CG) Obese or overweight female adults will be asked to avoid nuts, seeds and nut products, while they have a hypoenergetic diet.

Критериуми за подобност

Возраст подобни за студии	18 Years До 18 Years
Полови квалификувани за студии	Female
Прифаќа здрави волонтери	Да
Критериуми	Inclusion Criteria: - Must be female - Must be 18-45 years of age. - Must have Body mass index (BMI) between 27-35 kg/ m². - Must be able to have moderate exercise. - Must be interested to have weight loss. Exclusion Criteria: - Have allergy to nuts - Participating in a research project involving weight loss or physical activity in the previous six months. - Pregnancy or lactation during the previous 6 months, or planned pregnancy in the next six months. - Taking medication that could affect metabolism or change body weight. - Report heart problems, chest pain, and cancer within the last five years. - Smoking - Menopause - Diagnosis of any chronic disease such as fatty liver, cancer, chemo/radio therapy, heart disease, immune compromised conditions, abnormal thyroid hormone level.

Исход

Мерки на примарниот исход

1. Weight [12 Weeks]

Body weight was taken to the nearest 0.1 kg using a digital calibrated scale (Omron Health Care, Hoofddorp, Netherland), whilst subjects wore light clothing and no shoes.

Секундарни мерки на исходот

1. Waist circumference [12 Weeks]

Waist circumference (WC) was measured with a rigid measuring tape and recorded to the nearest 0.5 cm. WC was measured at the smallest horizontal circumference between the ribs and iliac crest (the natural waist), or, in case of an indeterminable waist narrowing, halfway between the lower rib and the iliac crest.

2. fasting blood glucose [12 Weeks]

Fasting plasma glucose (FPG) were measured using the enzymatic colorimetric method.

3. HbA1c [12 Weeks]

Glycated hamoglobin (HbA1c) was measured by a colorimetric method after an initial separation by ion exchange chromatography (Biosystem, Barcelona, Spain).

4. HOMA-IR [12 Weeks]

Insulin resistance was evaluated by homeostasis model assessment of insulin resistance (HOMA-IR), which was calculated by using the following formula HOMA-IR = [fasting insulin (mU/l) × FPG (mmol/l)]/22.5

5. lipid profiles [12 Weeks]

Biochemical analysis of the serum total cholesterol (TC), triglyceride (TG), and high-density lipoprotein (HDL) cholesterol was carried out on a Selectra E auto analyzer (Vita Laboratory, Netherlands) following standard procedures of the Pars Azmoon diagnostic kits (Iran). The LDL cholesterol was calculated using the Friedewald formula. LDL cholesterol = TC - HDL cholesterol + (TG ÷ 2.2)

6. liver function tests [12 Weeks]

AST ALT

7. Insulin [12 Weeks]

Insulin was measured by using a radioimmunoassay with 125I-labeled human insulin and a human insulin antiserum in an immunoradiometric assay (IRMA) (Biosource, Dorest, Belgium) with a gamma-counter system (Gamma I; Genesys).

Effects of Almond Versus Pistachio on Weight Loss

Клучни зборови

дебелина

pistacia

ф’стак

губење на тежина