Metabolic Syndrome and Female Breast Cancer

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Спонзори

Catholic University of Pelotas

КЛИНИЧКО ИСПИТУВАЊЕ: NCT02282592

BioSeek: NCT02282592

Клучни зборови

Апстракт

The role among metabolic syndrome and breast cancer risk is not well understood and must be further explored. The objective of this study is to evaluate the association between metabolic syndrome and breast cancer in Southern Brazil. In this case-control study, breast cancer patients and controls without malignant disease, matched for age (±5 years) and menopausal status, were interviewed and asked to make a glucose, HDL-cholesterol and triglycerides test. Waist circumference and blood pressure were measured using standardized procedures. Metabolic Syndrome was considered by NCEP ATP III (2001) and IDF (2006) definitions. Cases and controls were compared in relation to the presence of diagnosed MetS (yes/no), number of metabolic abnormalities identified (1 to 5) for each definition, and according to each metabolic abnormality cutoff point.

Датуми

Последен пат проверено:	09/30/2014
Прво доставено:	10/16/2014
Поднесено е проценето запишување:	10/30/2014
Прво објавено:	11/03/2014
Последното ажурирање е доставено:	10/30/2014
Последно ажурирање објавено:	11/03/2014
Крај на датумот на започнување на студијата:	10/31/2013
Проценет датум на примарно завршување:	07/31/2014
Проценет датум на завршување на студијата:	09/30/2014

Состојба или болест

Breast Cancer

Интервенција / третман

Other: Observation about the presence of metabolic syndrome

Фаза

Групи за раце

Рака	Интервенција / третман
Cases newly diagnosed (within 6 months) breast cancer patients, before adjuvant or neoadjuvant treatment.
Controls patients without any malignant disease, matched for age an menopausal status with cases.

Критериуми за подобност

Полови квалификувани за студии	Female
Метод на земање примероци	Non-Probability Sample
Прифаќа здрави волонтери	Да
Критериуми	Inclusion Criteria: - For cases: having newly diagnosed breast cancer without adjuvant or neoadjuvant treatment; - For controls: having no evidence of cancer; be matched for age and menopausal status with controls Exclusion Criteria: - Women with a recidivated tumor, HIV infection, renal, heart or liver disease, hypothyroidism or hyperthyroidism, mobility or neurological limitations, chronicle use of corticosteroids, pacemakers or identified with severe edema were excluded.

Исход

Мерки на примарниот исход

1. Odds Ratio for Breast Cancer according to the presence of Metabolic Syndrome and its components [Participants will be evaluated only once before the first appointment with the oncologist (cases with a biopsy) and gynecologist (controls). The blood test results for Metabolic Syndrome parameters were collected in an expected average of 30 days.]