Bananas as an Energy Source During Exercise: a Metabolomics Approach

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Спонзори

Appalachian State University

Соработници

Dole Food Company

КЛИНИЧКО ИСПИТУВАЊЕ: NCT01581190

BioSeek: nct01581190

Клучни зборови

Апстракт

This study compared the acute effect of ingesting bananas (BAN) versus a 6% carbohydrate drink (CHO) on 75-km cycling performance and post-exercise inflammation, oxidative stress, and innate immune function using traditional and metabolomics-based profiling.

Опис

Trained cyclists (N=14) completed two 75-km cycling time trials (randomized, crossover) while ingesting BAN or CHO (0.2 g/kg carbohydrate every 15 min). Pre-, post-, and 1-h-post-exercise blood samples were analyzed for glucose, granulocyte (GR) and monocyte (MO) phagocytosis (PHAG) and oxidative burst activity, nine cytokines, F2-isoprostanes, ferric reducing ability of plasma (FRAP), and metabolic profiles using gas chromatography-mass spectrometry.

Датуми

Последен пат проверено:	03/31/2012
Прво доставено:	04/13/2012
Поднесено е проценето запишување:	04/17/2012
Прво објавено:	04/19/2012
Последното ажурирање е доставено:	04/17/2012
Последно ажурирање објавено:	04/19/2012
Крај на датумот на започнување на студијата:	08/31/2011
Проценет датум на примарно завршување:	10/31/2011
Проценет датум на завршување на студијата:	10/31/2011

Состојба или болест

Intense Exercise

Интервенција / третман

Dietary Supplement: Bananas versus 6% carbohydrate beverage

Фаза

Групи за раце

Рака	Интервенција / третман
Experimental: Bananas versus 6% carbohydrate beverage	Dietary Supplement: Bananas versus 6% carbohydrate beverage Trained cyclists (N=14) completed two 75-km cycling time trials (randomized, crossover) while ingesting BAN or CHO (0.2 g/kg carbohydrate every 15 min).

Критериуми за подобност

Возраст подобни за студии	18 Years До 18 Years
Полови квалификувани за студии	Male
Прифаќа здрави волонтери	Да
Критериуми	Inclusion Criteria: - Male - Ages 18-45 years - Cyclists, road racing experience. - Willing to avoid the use of supplements, herbs, medications during the study. Exclusion Criteria: - Female - Over the age of 45 years - No cycling racing experience - Using supplements and medications during the study

Исход

Мерки на примарниот исход

1. Performance and fuel substrate utilization as measured through metabolomics [Up to 6 months]

Will measure shifts in metabolites following 75-km cycling while ingesting bananas or 6% carbohydrate beverage. The shift in metabolites will be assessed using GC-MS. Time frame from date of randomization until the last samples are collected and analyzed will be up to six months.

Секундарни мерки на исходот

1. Exercise-induced inflammation. [up to 6 months]

Cytokine panel (IL-6, IL-8, IL-10, TNF-alpha) before and after cycling 75-km; measured with Meso Scale Discovery in pg/ml. Time frame from randomization until the last samples are collected and analyzed will be up to six months.