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acromegaly/албумин

Врската е зачувана во таблата со исечоци
НаписиКлинички испитувањаПатенти
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Effects of growth hormone excess on glycated albumin concentrations: Analysis in acromegalic patients.

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BACKGROUND Glycated albumin (GA) does not reflect glycemic control in patients with disorders of albumin metabolism. In the present study, we examined GA concentrations in acromegalic patients with growth hormone (GH) excess. METHODS We studied the hormonal status of 29 acromegalic patients (10

Effect of growth hormone and insulin-like growth factor I on urinary albumin excretion: studies in acromegaly and growth hormone deficiency.

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Glomerular hyperfiltration is a characteristic feature of acromegaly but it is uncertain whether albuminuria is elevated in this disease. To investigate the role of abnormal growth hormone (GH) and insulin-like growth factor I (IGF-I) levels on urinary protein excretion, we measured the overnight

Metabolism and transcapillary escape rate of albumin in acromegaly.

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Exercise-induced microalbuminuria in patients with active acromegaly: acute effects of slow-release lanreotide, a long-acting somatostatin analog.

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Recent clinical studies have demonstrated an increase of urinary albumin excretion (UAE) at rest in acromegalic patients and, on the other hand, a reduced UAE in patients with growth hormone (GH) deficiency. Physical exercise is known to induce abnormal UAE in patients with diabetes, probably

The effect of albumin fusion patterns on the production and bioactivity of the somatostatin-14 fusion protein in Pichia pastoris.

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Somatostatin is a natural inhibitor of growth hormone, and its analogues are clinically used for the therapy of acromegaly, gigantism, thyrotropinoma, and other carcinoid syndrome. However, natural somatostatin is limited for clinical usage because of its short half-life in vivo. Albumin fusion

The effect of somatostatin analogs on vitamin D and calcium concentrations in patients with acromegaly.

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OBJECTIVE The goals of this study were to determine: (1) 25OH vitamin D (25OHD) and calcium levels in patients with acromegaly and their association with insulin-like growth factor (IGF-1) and (2) whether somatostatin analog (SSA) therapy effects calcium and 25OHD levels. METHODS 125 patients with

Association of clinical and laboratory parameters with ambulatory arterial stiffness index in acromegaly patients.

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UNASSIGNED In this study, we determined the relationship between the ambulatory arterial stiffness index (AASI) and clinical and laboratory parameters in patients with acromegaly. UNASSIGNED Sixty-five patients with acromegaly, who visited to Dicle University Medical Faculty Department of

Multiple myeloma in a patient with acromegaly.

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Acromegaly is a slowly progressing condition resulting from excess growth hormone (GH), generally caused by a GH-secreting pituitary adenoma. Cancer is the third most common cause of mortality in patients with acromegaly, and insulin-like growth factor 1 (IGF-1) is known to influence tumor formation

A comparison of the effect of levodopa and somatostatin on the plasma levels of growth hormone, insulin, glucagon and prolactin in acromegaly.

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The acute suppressive effects of L-dopa and somatostatin (growth hormone release inhibiting hormone) on the elevated plasma GH concentrations of seven patients with acromegaly were compared. In addition the effects of the two agents on fasting concentrations of plasma glucose, insulin, glucagon and

Hypertension-related factors in patients with active and inactive acromegaly.

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BACKGROUND There are several complications of the cardiovascular system caused by acromegaly, especially hypertension. OBJECTIVE To evaluate hypertension characteristics in patients with cured/controlled acromegaly and with the active disease. METHODS Cross-sectional study of the follow-up of

Hypoproteinemia in acromegaly.

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Although it is well known that growth hormone may influence protein metabolism, few investigations have been undertaken on serum protein levels in acromegaly; recently hypoglobulinemia has been observed in this endocrine disorder. In 28 acromegalic patients and 56 control subjects sera have been

The effect of albumin fusion structure on the production and bioactivity of the somatostatin-28 fusion protein in Pichia pastoris.

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Somatostatin, a natural inhibitor of growth hormone (GH), and its analogs have been used in clinical settings for the treatment of acromegaly, gigantism, thyrotropinoma, and other carcinoid syndromes. However, natural somatostatin is limited for clinical usage because of its short half-life in vivo.

Effect of hyperprolactinaemia due to pituitary tumour on serum albumin, protein and oncotic pressure.

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1. Serum albumin, total protein, oncotic pressure and osmolality were measured in a group of patients with hyperprolactinaemia due to a prolactin secreting tumour, normal subjects and normoprolactinaemic acromegalic patients. 2. A significant increase in albumin, total protein and oncotic pressure

Kidney function in acromegaly.

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Creatinine clearance and daily urinary albumin and beta2-microglobulin excretion rates (radio-immunoassays) were measured several times in 14 patients with acromegaly. Eleven patients were treated with bromocriptine, 5 to 55 mg/day. The activity of the disease was assessed by measuring urinary

Effect of active acromegaly and its treatment on parathyroid circadian rhythmicity and parathyroid target-organ sensitivity.

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BACKGROUND Patients with active acromegaly have increased bone turnover and skeletal abnormalities. Biochemical cure of acromegaly may represent a functional GH-deficient state and result in cortical bone loss. Reduced PTH target-organ sensitivity occurs in adult GH deficiency and may underlie the
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