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beta-thalassemia/калиум
Врската е зачувана во таблата со исечоци
Страница 1 од 17 резултати
Renal abnormalities in patients with sickle cell-beta thalassemia.
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We examined renal abnormalities in Greek patients with sickle-cell beta thalassemia (S-beta thal). A total of 17 patients aged 16-59 years suffering from S-beta thal and 17 age- and sex-matched healthy controls were studied. In all individuals we carried out a detailed study of renal function
A prospective study of tubular dysfunction in pediatric patients with Beta thalassemia major receiving deferasirox.
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BACKGROUND
Beta thalassemia major is a lifelong transfusion-dependent disorder. Transfusion-dependent thalassemia patients are prone to develop renal dysfunction due to iron overload, chronic anemia, and/or chelation therapy.
METHODS
In this prospective study, thalassemia patients who fitted
Influence of hemoglobin precipitation on erythrocyte metabolism in alpha and beta thalassemia.
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Certain aspects of the metabolism of centrifuged young and old erythrocytes in hemoglobin H disease have been examined and compared with similar studies of beta thalassemia and normal cells. Glycolysis, hexose monophosphate shunt activity (HMPS), potassium flux, and glutathione (GSH) content were
Hematological and biochemical status of Beta-thalassemia major patients in Bangladesh: A comparative analysis.
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BACKGROUND
Thalassemia is one of the most common hereditary disorders and Beta-thalassemia major is its severe form. The present study is concerned with the analysis of liver function, thyroid function and estimation of critical serum ions as well as hematological characteristics in beta-thalassemia
Hematological and biochemical evaluation of β-thalassemia major (βTM) patients in Gaza Strip: A cross-sectional study.
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A Novel Variant with Positive Natural Selection Influenced Hb A2 Levels in Chinese Individuals with β-Thalassemia.
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β-Thalassemia (β-thal) is the most common inherited hemolytic anemia worldwide. Elevated Hb A2 is a mark of β-thal carriers. The aim of this study was to identify the pathogenic variants associated with the Hb A2 levels. One thousand and thirty β-thal carriers were recruited for this study. Using
Renal Hemosiderosis among Iranian Transfusion Dependent β-Thalassemia Major Patients.
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Background: In recent years, the success in management of thalassemic patients, has allowed for some previously unrecognized complications including renal abnormalities to emerge. This prospective study aimed to investigate kidney iron overload by means of MRI T2* and also renal function based on
Urinary early kidney injury molecules in children with beta-thalassemia major.
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BACKGROUND
The aim of this study was to investigate novel urinary biomarkers including N-acetyl-β-D-glucosaminidase (NAG), neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (KIM-1), and liver-type fatty acid binding protein (L-FABP) in children with β-thalassemia major
Early markers of renal dysfunction in patients with beta-thalassemia major.
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Studies of renal involvement in thalassemia syndromes have been varied and few. The most important cause of mortality and morbidity in these patients is organ failure due to iron deposition. We report here a cross-sectional study carried out between February 2005 and February 2006 on all
Renal function in pediatric patients with beta-thalassemia major.
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In patients with beta-thalassemia major, the most important cause of mortality and morbidity is organ failure due to deposits of iron. In this study, the nature of the kidney injury and possible pathogenetic factors were investigated. Seventy children with beta-thalassemia major and 14 age and
Renal function in children with beta-thalassemia major and thalassemia intermedia.
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In beta-thalassemia, profound anemia and severe hemosiderosis cause functional and physiological abnormalities in various organ systems. In recent years, there have been few published studies demonstrating proteinuria, aminoaciduria, low urine osmolality, and excess secretion of the tubular damage
Renal tubular dysfunction in pediatric patients with beta-thalassemia major.
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To evaluate the prevalence of renal tubular dysfunction in children with β-thalassemia (β-T) major, we studied the glomerular and tubular function in 140 children with β-T major and compared them to a healthy control group at our center from May 2007 to April 2008. Fresh first morning samples were
Kidney function tests in children with beta-thalassemia minor in Zahedan, southeast of Iran.
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There is little information regarding kidney function in patients with beta-thalassemia minor. In this study we investigated kidney function tests in 50 children with beta-thalassemia minor (22 boys and 28 girls). Twenty-four-hour urine samples were collected and analyzed for sodium, potassium,
Hyperchloremic metabolic acidosis due to deferasirox in a patient with beta thalassemia major.
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OBJECTIVE
To report a case of hyperchloremic metabolic acidosis in a patient with beta thalassemia major secondary to treatment with deferasirox due to iron overload.
METHODS
A 58-year-old white female with beta thalassemia major was admitted with fever, fatigue, abnormal liver function test
Renal function in transfusion-dependent pediatric beta-thalassemia major patients.
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OBJECTIVE
In this study, the relationship between glomerular and tubular function and creatinine, glomerular filtration rate (GFR) and urine NAG in thalassemia major patients aged 7-16 years was investigated.
METHODS
This is a case-control study comprising 280 individuals [144 (51·4%), males; 136
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